Correction



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Am Fam Physician. 2001 Sep 15;64(6):927-928.

Table 2 of the article “Topical Fluoroquinolones for Eye and Ear” (October 15, 2000, page 1872) contained an error regarding the recommended use of the topical medication ciprofloxacin-hydrocortisone (Cipro HC). The table incorrectly states that Cipro HC, a nonsterile solution, is recommended for use in patients with acute otitis externa and acute otitis media with tympanic membrane perforation. According to the 55th edition of the Physicians’ Desk Reference, the use of Cipro HC is actually contraindicated in patients with a perforated tympanic membrane. However, the table correctly indicates that Floxin, a 0.3 percent sterile solution of ofloxacin, is indicated for use in patients with acute otitis externa, chronic suppurative otitis media with perforations and acute otitis media with tympanostomy tubes. The corrected table is reprinted above.

TABLE 2

Recommended Treatment Regimens for Ear Infections

Condition Drug Dosage* Duration Cost†

Acute otitis externa

Ciprofloxacin-hydrocortisone (Cipro HC)

Adult: 3 drops, twice daily

7 to 10 days

$59.00‡/10 mL

Child: 3 drops, twice daily

Ofloxacin(Floxin)

Adult: 10 drops, twice daily

7 to 10 days

34.00‡/5 mL

Child: 5 drops, twice daily

Polymyxin B– neomycin– hydrocortisone§ (Cortisporin)

Adult: 5 drops, three to four times daily

7 to 10 days

Brand: 42.00 (solution or suspension)/10 mL

Child: 4 drops, three to four times daily

Generic: 10.00 to 28.00/10 mL

Acute otitis media with tympanostomy tubes

Ofloxacin

Adult: 5 drops, twice daily

10 to 14 days

Same as above

Child: 5 drops, twice daily

Polymyxin B– neomycin– hydrocortisone§

Adult: 5 drops, three to four times daily

10 to 14 days

Same as above

Child: 4 drops, three to four times daily

Chronic suppurative otitis media

Ofloxacin

Adult: 10 drops, twice daily

14 to 21 days

Same as above

Child: 5 drops, twice daily

Polymyxin B– neomycin– hydrocortisone§

Not recommended

Same as above


*—Adult = 12 years and older; child = one to 11 years.

†—Costs are given for one-bottle supply. Estimated cost to pharmacist based on average wholesale prices, rounded to nearest dollar amount in Red book. Montvale, NJ: Medical Economics Data, 2000.

‡—Generic not available.

§—Examples: Cortisporin, Colymycin, Pediotic.

TABLE 2   Recommended Treatment Regimens for Ear Infections

View Table

TABLE 2

Recommended Treatment Regimens for Ear Infections

Condition Drug Dosage* Duration Cost†

Acute otitis externa

Ciprofloxacin-hydrocortisone (Cipro HC)

Adult: 3 drops, twice daily

7 to 10 days

$59.00‡/10 mL

Child: 3 drops, twice daily

Ofloxacin(Floxin)

Adult: 10 drops, twice daily

7 to 10 days

34.00‡/5 mL

Child: 5 drops, twice daily

Polymyxin B– neomycin– hydrocortisone§ (Cortisporin)

Adult: 5 drops, three to four times daily

7 to 10 days

Brand: 42.00 (solution or suspension)/10 mL

Child: 4 drops, three to four times daily

Generic: 10.00 to 28.00/10 mL

Acute otitis media with tympanostomy tubes

Ofloxacin

Adult: 5 drops, twice daily

10 to 14 days

Same as above

Child: 5 drops, twice daily

Polymyxin B– neomycin– hydrocortisone§

Adult: 5 drops, three to four times daily

10 to 14 days

Same as above

Child: 4 drops, three to four times daily

Chronic suppurative otitis media

Ofloxacin

Adult: 10 drops, twice daily

14 to 21 days

Same as above

Child: 5 drops, twice daily

Polymyxin B– neomycin– hydrocortisone§

Not recommended

Same as above


*—Adult = 12 years and older; child = one to 11 years.

†—Costs are given for one-bottle supply. Estimated cost to pharmacist based on average wholesale prices, rounded to nearest dollar amount in Red book. Montvale, NJ: Medical Economics Data, 2000.

‡—Generic not available.

§—Examples: Cortisporin, Colymycin, Pediotic.


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