Please note: This information was current at the time of publication. But medical information is always changing, and some information given here may be out of date. For regularly updated information on a variety of health topics, please visit familydoctor.org, the AAFP patient education website.
Information from Your Family Doctor
FREE PREVIEW. AAFP members and paid subscribers: Log in to get free access. All others: Purchase online access.
FREE PREVIEW. Purchase online access to read the full version of this article.
Am Fam Physician. 2003 Aug 15;68(4):717-718.
What is Crohn's disease?
Crohn's disease causes ulcers to form in the gastrointestinal (GI) tract anywhere from the mouth to the anus. Symptoms include stomach cramps and pain that comes and goes, diarrhea, and blood in your stool. Other symptoms include weight loss, nausea, joint pain, and feeling tired. Some people with Crohn's disease have severe symptoms, while others have less severe symptoms. Some people with the disease have long periods without symptoms, even without needing treatment. Others with more severe disease will need long-term treatment or even surgery.
Who gets Crohn's disease?
Almost 500,000 people in the United States have Crohn's disease. Anyone can get Crohn's disease, but it's more common in women, whites, and Jewish people. It is not known what causes Crohn's disease. It seems to run in families, but there is no known pattern of inheritance.
How can my doctor tell if I have Crohn's disease?
If your doctor thinks you may have Crohn's disease, he or she will ask you about your symptoms and do a complete exam to look for signs of the illness. If your symptoms and exam findings suggest that you may have Crohn's disease, your doctor may do some blood work. While no blood test can prove you have Crohn's disease, your blood might show anemia, salt imbalance, vitamin deficiency, or increased signs of inflammation. Your doctor also may order special x-rays or a procedure called endoscopy, which lets your doctor look at your colon or stomach to check for ulcers.
How is Crohn's disease treated?
The treatment of Crohn's disease depends on how bad it is and where it is in your GI tract. When the disease is mild, medicines called salicylates may help. Sulfasalazine (brand name: Azulfidine) and mesalamine (brand name: Rowasa) are the most common salicylates. Antibiotics such as metronidazole (brand name: Flagyl) and ciprofloxacin (brand name: Cipro) are also used to treat mild Crohn's disease.
Steroids are generally used for persons with more severe disease. In more aggressive disease, steroids may be used with immunosuppressants, or with a newer medicine called infliximab (brand name: Remicade). If you have very severe disease, you may need to stay in the hospital. Sometimes, surgery is needed, but it does not cure the disease.
What can I expect after treatment?
The success of treatment for Crohn's disease varies. While there is no known cure for the illness, many people have long periods without symptoms. Your doctor will need to see you regularly to check for signs of active disease or any disease complications. People with long-term disease may become depressed or have other mood disorders. Your doctor will check you for these problems as well.
Where can I get more information?
Crohn's and Colitis Foundation of America
386 Park Avenue South, 17th Floor
New York, NY 10016-8804
Telephone: 1-800-932-2423 or 1-212-685-3440
In addition, you can visit the National Digestive Diseases Information Clearinghouse atwww.niddk.nih.gov/health/digest/pubs/crohns/crohns.htm.
This handout is provided to you by your family doctor and the American Academy of Family Physicians. Other health-related information is available from the AAFP online at http://familydoctor.org.
This information provides a general overview and may not apply to everyone. Talk to your family doctor to find out if this information applies to you and to get more information on this subject.
Copyright © 2003 by the American Academy of Family Physicians.
This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Contact firstname.lastname@example.org for copyright questions and/or permission requests.
Want to use this article elsewhere? Get Permissions