BETH POTTER, M.D., KIRSTEN RINDFLEISCH, M.D., and CONNIE K. KRAUS, PHARM.D.

Sputum samples should be obtained from patients with findings of tuberculosis and those suspected of having active disease. Most patients are treated with eight weeks of a four-drug regimen; some require an added two-drug regimen for 18 weeks.

Patient information: "Tuberculosis: What You Should Know," p. 2235

CHARLES COLE, M.D., CRAIG SETO, M.D., and JOHN GAZEWOOD, M.D., M.S.P.H.

Plantar fasciitis is a common cause of heel pain. Many patients improve without intervention, although shoe inserts, stretching exercises, steroid injection, and
custom-made night splints may be beneficial.

Patient information: "Plantar Fasciitis: What You Should Know," p. 2247

SILVANA LAWVERE, PH.D., and MARTIN C. MAHONEY, M.D., PH.D.

This herbal preparation has been found to be superior to placebo and equivalent to standard antidepressants for the treatment of mild to moderate depression.

DANIEL J. WATTENDORF, MAJ, MC, USAF, and MAXIMILIAN MUENKE, M.D.

Males with an additional X chromosome (47,XXY) are infertile and have hypogonadism with gynecomastia and small testes. Early androgen replacement therapy may ameliorate many clinical findings.

GREGORY JUCKETT, M.D., M.P.H.

An understanding of other cultures can improve treatment adherence, patient care, and clinical outcomes. Respectful patient interactions are vital for making accurate diagnoses and negotiating treatment goals.

Editorial: "Culturally Competent Family Medicine: Transforming Clinical Practice and Ourselves," p. 2189

CHRISTINE HSIEH, M.D.

Symptoms of constipation often improve with increased fiber intake and laxatives; biofeedback and surgery may be necessary in some patients.

Patient information: "Constipation: What You Should Know," p. 2285