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Articles
382 Prevention of Recurrent Ischemic Stroke
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LORI M. DICKERSON, PharmD, PETER J. CAREK, MD, MS, and ROBERT GLEN QUATTLEBAUM, MD, MPH

ACF Stroke survivors have an average of 10 outpatient visits per year. At each visit, physicians should evaluate vascular risk factors (e.g., hypertension, diabetes, hypercholesterolemia) and lifestyle risk factors (e.g., obesity, smoking, alcohol use). Preventive therapy includes drug treatment, with surgical intervention in selected patients. CME

    Patient information: "Preventing Another Stroke: What You Should Know," p. 389
    
391 The Effect of Cytochrome P450 Metabolism on Drug Response, Interactions, and Adverse Effects
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TOM LYNCH, PharmD, and AMY PRICE, MD

Cytochrome P450 enzymes can be inhibited or induced by drugs, resulting in clinically significant drug-drug interactions that may cause unanticipated adverse effects or therapeutic failures. Knowledge of the drugs metabolized, as well as the most common inhibiting and inducing medications, can help reduce the possibility of adverse interactions. CME

    Editorial: "Is Genetic Testing for Cytochrome P450 Polymorphisms Ready for Implementation in Clinical Practice?" p. 348
    
397 Recommendations for Preconception Care
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MICHAEL C. LU, MD, MPH

Every woman of reproductive age who is capable of becoming pregnant is a candidate for preconception care, even if she is not planning to conceive. Most components of preconception care can be performed in the primary care setting. CME

   
405 Turner Syndrome: Diagnosis and Management
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THOMAS MORGAN, MD

The clinical manifestations of Turner syndrome vary; however, the syndrome should be considered in girls with short stature or primary amenorrhea. Complications and risk factors associated with Turner syndrome should be managed throughout the patient's life. CME

   


Departments
  
Keeping Up to Date
418 Clinical Evidence Concise EB CME

• Acute Renal Failure

430 Tips from Other Journals
439 Practice Guidelines
  
Answering Clinical Questions
339 Clinical Quiz
373 Cochrane for Clinicians
423 FPIN's Clinical Inquiries

• Angiotensin Blockade in Patients with Diabetic Nephropathy

425 Photo Quiz
437 Curbside Consultation

• Should Physicians Accept Gifts from Patients?

   
  
Commentary
320 Inside AFP
343 Letters to the Editor

• Importance of Influenza Vaccination for Children

348 Editorials
   
  
Medicine and Society
327 Newsletter
333 Quantum Sufficit
   
  
Patient Information
389 Preventing Another Stroke
   
 
Reader Services
323 Strength-of-Recommendation Taxonomy in AFP
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• Search available CME courses

403 Change-of-Address Form
417 Evidence-Based Medicine Glossary
448 Classified Information
  Information for Authors

ACF This article exemplifies the AAFP 2007 Annual Clinical Focus on management of chronic illness.

CMEThis article is included as part of this issue's continuing medical education (CME) activity. See Clinical Quiz, p. 339.

EB CME This logo designates clinical content that conforms to AAFP criteria for evidence-based continuing medical education (EB CME). EB CME is clinical content presented with practice recommendations supported by evidence that has been reviewed systematically by an AAFP-approved source.



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