POEMs

Intensive Lifestyle Intervention Fails to Improve Patient-Oriented Outcomes in Persons with Obesity and Diabetes



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Am Fam Physician. 2013 Dec 15;88(12):online.

Clinical Question

Does an intensive lifestyle intervention focused on weight loss and exercise improve outcomes in patients with diabetes mellitus?

Bottom Line

This large, well-designed trial failed to find a statistically significant improvement in patient-oriented outcomes in patients with diabetes, despite a fairly intensive lifestyle intervention and long-term follow-up. (Level of Evidence = 1b)

Synopsis

There is relatively little high-quality clinical trial evidence to support recommendations for weight loss and exercise in patients with type 2 diabetes. In this study, 5,145 adults, 45 to 75 years of age, with type 2 diabetes and a body mass index of at least 25 kg per m2 were randomized to receive an intensive lifestyle intervention (weekly visits providing group and individual counseling regarding calorie-reducing diet and exercise, with a goal of 7% weight loss and at least 175 minutes of exercise

POEMs (patient-oriented evidence that matters) are provided by Essential Evidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. For more information, please see http://www.essentialevidenceplus.com. Copyright Wiley-Blackwell. Used with permission.

For definitions of levels of evidence used in POEMs, see http://www.essentialevidenceplus.com/product/ebm_loe.cfm?show=oxford.

To subscribe to a free podcast of these and other POEMs that appear in AFP, search in iTunes for “POEM of the Week” or go to http://goo.gl/3niWXb.



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