Am Fam Physician. 2014 Jan 15;89(2):131-136.
In patients with low vitamin D levels, does vitamin D supplementation improve symptoms of depression?
Taken in aggregate, symptoms of depression do not improve in patients with low vitamin D levels when given vitamin D supplementation any more than when given placebo. There may be a benefit in patients with low vitamin D levels and mild to moderate depression. (Level of Evidence = 1b–)
This study was conducted in Norway, where researchers started by identifying patients with depressive symptoms and low vitamin D levels (< 22 ng per mL [< 55 nmol per L]). The
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