POEMs

Influenza Vaccine Reduces Risk of Adverse Cardiovascular Events in High-Risk Patients



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Am Fam Physician. 2014 Feb 1;89(3):224-225.

Clinical Question

Does the influenza vaccine lower the risk of major adverse cardiovascular events in adults with coronary disease?

Bottom Line

This meta-analysis found that the influenza vaccine is associated with a significantly lower risk of major adverse cardiovascular events in adults with coronary disease. The benefit of influenza vaccination is strongest in adults with a history of recent acute coronary syndrome within the previous six months (number needed to treat [NNT] = 8). (Level of Evidence = 1a)

Synopsis

These investigators searched multiple sources, including Medline, Embase, the Cochrane Register, reference lists of eligible articles, clinicaltrials.gov, and conference abstracts without language restrictions for all

POEMs (patient-oriented evidence that matters) are provided by Essential Evidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. For more information, please see http://www.essentialevidenceplus.com. Copyright Wiley-Blackwell. Used with permission.

For definitions of levels of evidence used in POEMs, see http://www.essentialevidenceplus.com/product/ebm_loe.cfm?show=oxford.

To subscribe to a free podcast of these and other POEMs that appear in AFP, search in iTunes for "Poem of the Week" or go to http://goo.gl/3niWXb.



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