High-Potency Topical Corticosteroids Effective for Alopecia Areata in Children
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Am Fam Physician. 2014 Jun 1;89(11):913.
Are high-potency topical corticosteroids more effective than low-potency corticosteroids for alopecia areata in children?
Clobetasol propionate, 0.05%, applied in a thin layer for six weeks on, six weeks off, is a highly effective and safe treatment for alopecia areata in children; hydrocortisone, 1%, is not. (Level of Evidence = 1b)
There are limited randomized controlled trial data regarding treatment of alopecia areata. In this trial, 41 children (age range = two to 16 years) who had at least 10% scalp involvement were randomized to receive a high-potency topical corticosteroid (clobetasol propionate, 0.05%) or a low-potency topical corticosteroid
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