Am Fam Physician. 2015 Aug 1;92(3):228.
Can the way dishes are washed affect the development of allergies in children?
These results add further credence to the idea that the gastrointestinal system plays a big role in the development of our immune system (i.e., the hygiene hypothesis). Washing children's bottles and eating utensils by hand instead of using an automatic dishwasher was associated with a lower risk of developing an allergic disorder. The authors stop short of recommending low hygienic standards, but they suggest that fastidiousness might not allow the immune system to learn how to self-modulate. (Level of Evidence = 2b)
The goal of this wide-ranging study was to see whether exposure to microbes early in life affected the development of allergies. The Swedish investigators sent questionnaires to parents of 1,029 children, seven to eight years of age, in a single city, asking about each child's history of allergy, including any diagnosis of eczema, asthma, or allergic rhinoconjunctivitis, as well as asking about eating habits. To test for dietary microbes, the researchers asked parents about how they washed their dishes (using a dishwasher or by hand); their use of farm-purchased milk, eggs, or unpasteurized milk; whether their diet included fermented foods (e.g., sauerkraut) or home-cooked foods; and the duration of their breastfeeding.
Most of the children attended day care and one-third had a pet, but only 6% lived in a household in which a parent reported smoking inside. After analyzing all these factors to look for associations, hand dishwashing, which occurred in only 12% of households, was associated with the greatest reduced risk of allergic disease development (odds ratio = 0.57; 95% confidence interval, 0.37 to 0.85). The risk was further reduced in a dose-response pattern if the children were also served fermented food and if the family bought food directly from farms. The associations remained after adjusting for socioeconomic factors.
Study design: Cross-sectional
Funding source: Foundation
Reference: Hesselmar B, Hicke-Roberts A, Wennergren G. Allergy in children in hand versus machine dishwashing. Pediatrics. 2015; 135( 3): e590– e597.
POEMs (patient-oriented evidence that matters) are provided by EssentialEvidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. For more information, please see http://www.essentialevidenceplus.com. Copyright Wiley-Blackwell. Used with permission.
For definitions of levels of evidence used in POEMs, see http://www.essentialevidenceplus.com/product/ebm_loe.cfm?show=oxford.
To subscribe to a free podcast of these and other POEMs that appear in AFP,search in iTunes for “POEM of the Week” or go to http://goo.gl/3niWXb.
This series is coordinated by Sumi Sexton, MD, Associate Medical Editor.
A collection of POEMs published in AFP is available at http://www.aafp.org/afp/poems.
Want to use this article elsewhere? Get Permissions
More in AFP
MOST RECENT ISSUE
Oct 1, 2016
Access the latest issue of American Family Physician