Steroids Beneficial As Adjunctive Treatment for Community-Acquired Pneumonia
Am Fam Physician. 2016 Feb 1;93(3):227.
Should steroids be used as adjunctive therapy for patients with community-acquired pneumonia (CAP)?
Moderate-quality to high-quality evidence suggests that steroids, when added to antibiotics and usual care, can improve outcomes in the treatment of CAP. Benefits include reduced hospital length of stay, decreased time to clinical stability, and lower rates of mechanical ventilation and acute respiratory distress syndrome. Steroids may also play a role in preventing deaths, especially in patients with severe CAP; however, the certainty of this evidence is not as clear. Given varying treatment regimens used in the individual studies, the appropriate steroid formulation, dosage, and duration of steroids cannot be elucidated from the current set of data. (Level of Evidence = 1a)
These authors searched Medline, Embase, and the Cochrane Register to find
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