Am Fam Physician. 2016 Mar 15;93(6):492.
Are electronic cigarettes (e-cigarettes) effective for smoking cessation in adults?
Nicotine-containing e-cigarettes may be more effective than placebo devices for smoking cessation. They may also aid in smoking reduction, but the quality of available evidence is low. (Strength of Recommendation [SOR]: B, based on a systematic review.) Little is known about their safety.
A systematic review pooled two randomized controlled trials (RCTs) and found six-month quit rates of 9% for e-cigarettes compared with 4% for placebo (N = 662; relative risk [RR] = 2.29; 95% confidence interval [CI], 1.05 to 4.96).1 The number of participants who reported reducing their cigarette consumption by at least 50% was 36% in the nicotine-containing e-cigarette group compared with 27% in the placebo group (N = 612; RR = 1.31; 95% CI, 1.02 to
REFERENCESshow all references
1. McRobbie H, et al. Electronic cigarettes for smoking cessation and reduction. Cochrane Database Syst Rev. 2014;(12):CD010216....
2. Bullen C, et al. Electronic cigarettes for smoking cessation. Lancet. 2013;382(9905):1629–1637.
3. Caponnetto P, et al. EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as tobacco cigarettes substitute. PLoS One. 2013;8(6):e66317.
4. U.S. Food and Drug Administration. Warning letters issued to e-cigarette companies illegally making FDA-related claims. http://www.fda.gov/tobaccoproducts/newsevents/ucm442497.htm. Accessed January 16, 2016.
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