Preexposure Prophylaxis with Tenofovir/Emtricitabine Prevents HIV Infection in Men Who Have Unprotected Anal Intercourse
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Am Fam Physician. 2016 Mar 15;93(6):520.
Among men who have unprotected anal intercourse, does the combination of tenofovir/emtricitabine (Truvada) taken before and after intercourse reduce the risk of human immunodeficiency virus (HIV) infection?
Preexposure prophylaxis in high-risk men who have unprotected anal intercourse reduces the likelihood of developing HIV (number needed to treat = 17 per year). Participants averaged 15 pills per month, which costs approximately $700 per month ($8,400 per year). Condoms would be a much more cost-effective way to prevent HIV infection (although condoms were not compared with medications in this study). (Level of Evidence = 1b)
The researchers identified 400 HIV-negative men who had unprotected
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