Low High-Sensitivity Troponin I Level Accurate in Identifying Patients at Low Risk of Cardiac Events


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Am Fam Physician. 2016 Apr 15;93(8):704a-705.

Clinical Question

Is the high-sensitivity troponin I assay accurate in identifying patients with suspected acute coronary syndromes who are at low risk of cardiac events?

Bottom Line

The high-sensitivity troponin I assay used in this study was fairly accurate in identifying patients with chest pain who are at low risk of cardiac events. (Level of Evidence = 1c−)


These authors conducted a two-part study in adults presenting to the emergency department with suspected acute coronary syndromes. Each of the participating departments had been randomized into the standard care arms of trials designed to determine if high-sensitivity troponin I levels will influence

POEMs (patient-oriented evidence that matters) are provided by EssentialEvidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. For more information, please see http://www.essentialevidenceplus.com. Copyright Wiley-Blackwell. Used with permission.

For definitions of levels of evidence used in POEMs, see http://www.essentialevidenceplus.com/product/ebm_loe.cfm?show=oxford.

To subscribe to a free podcast of these and other POEMs that appear in AFP,search in iTunes for “POEM of the Week” or go to http://goo.gl/3niWXb.

This series is coordinated by Sumi Sexton, MD, Associate Deputy Editor.

A collection of POEMs published in AFP is available at http://www.aafp.org/afp/poems.


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Oct 15, 2016

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