POEMs

Single-Dose Dexamethasone Equals Three Days of Steroids in Children with Acute Asthma

 


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Am Fam Physician. 2016 Aug 15;94(4):317.

Clinical Question

In children with acute exacerbation of asthma, is a single dose of corticosteroid as effective as three days of treatment?

Bottom Line

In addition to usual beta-agonist treatment, a single dose of oral dexamethasone is as effective as three days of prednisolone (with less vomiting) in decreasing respiratory symptoms without increasing hospitalizations, follow-up visits, and days lost from school. Additional treatment with a steroid was more common in the group receiving the single dose of dexamethasone. (Level of Evidence = 1b)

Synopsis

These Irish investigators enrolled 226 children (for a total of 245 enrollments; some were enrolled twice) between

POEMs (patient-oriented evidence that matters) are provided by EssentialEvidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. For more information, please see http://www.essentialevidenceplus.com. Copyright Wiley-Blackwell. Used with permission.

For definitions of levels of evidence used in POEMs, see http://www.essentialevidenceplus.com/product/ebm_loe.cfm?show=oxford.

To subscribe to a free podcast of these and other POEMs that appear in AFP, search in iTunes for “POEM of the Week” or go to http://goo.gl/3niWXb.

This series is coordinated by Sumi Sexton, MD, Associate Deputy Editor.

A collection of POEMs published in AFP is available at http://www.aafp.org/afp/poems.



 

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