Am Fam Physician. 2016 Aug 15;94(4):317.
In children with acute exacerbation of asthma, is a single dose of corticosteroid as effective as three days of treatment?
In addition to usual beta-agonist treatment, a single dose of oral dexamethasone is as effective as three days of prednisolone (with less vomiting) in decreasing respiratory symptoms without increasing hospitalizations, follow-up visits, and days lost from school. Additional treatment with a steroid was more common in the group receiving the single dose of dexamethasone. (Level of Evidence = 1b)
These Irish investigators enrolled 226 children (for a total of 245 enrollments; some were enrolled twice) between
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