Stop Using Antipsychotics to Treat or Prevent Delirium—They Are No Better Than Placebo
Am Fam Physician. 2016 Aug 15;94(4):318-319.
Are antipsychotic medications effective in preventing or treating delirium in hospitalized patients?
The available data indicate that antipsychotic medications are ineffective in preventing or treating delirium in hospitalized patients. Because there are concerns about falls and extrapyramidal effects with antipsychotics (not reported in this study), we should stop using them. (Level of Evidence = 1a−)
These authors searched several databases and a clinical trials registry to identify randomized trials and cohort studies that evaluated the use of antipsychotic medications for preventing or treating delirium in hospitalized adults. Two authors independently
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