Step-by-Step Approach to Ruling Out Infant Infection Is Accurate
Am Fam Physician. 2016 Dec 1;94(11):933.
Is the Step-by-Step approach useful for ruling out systemic infection in young low-risk infants?
The Step-by-Step approach, using a basic physical examination and readily available urine and blood tests (without lumbar puncture; see the Synopsis section), can successfully identify low-risk infants younger than 90 days who will not need empiric antibiotic treatment and lumbar puncture. However, this approach has not been studied (nor has any other approach, I believe) in a randomized controlled trial to see whether it is effective at decreasing lumbar punctures or hospital admissions. (Level of Evidence = 1a)
This study was conducted at 11 European pediatric emergency departments. The researchers
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