POEMs

Cervical Treatment Associated with Adverse Obstetric Outcomes

 

Am Fam Physician. 2016 Dec 1;94(11):933a-936.

Clinical Question

Is cervical treatment for preinvasive and early invasive disease associated with subsequent adverse obstetric outcomes?

Bottom Line

Cervical treatments for dysplasia and early cervical carcinoma are associated with subsequent risk of preterm birth. Excisional treatments carry higher risk than ablative treatments, and multiple treatments carry higher risk than single treatments. The frequency and severity of prematurity-related outcomes increase with increasing cone depth and volume. (Level of Evidence = 2a)

Synopsis

This report is a meta-analysis of observational studies to assess the associations between local treatments for cervical intraepithelial neoplasia or early invasive carcinoma and subsequent obstetric outcomes. The authors included 71 studies (70 cohort, one case-control) with 65,082 treated women

POEMs (patient-oriented evidence that matters) are provided by EssentialEvidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. For more information, please see http://www.essentialevidenceplus.com. Copyright Wiley-Blackwell. Used with permission.

For definitions of levels of evidence used in POEMs, see http://www.essentialevidenceplus.com/product/ebm_loe.cfm?show=oxford.

To subscribe to a free podcast of these and other POEMs that appear in AFP, search in iTunes for “POEM of the Week” or go to http://goo.gl/3niWXb.

This series is coordinated by Sumi Sexton, MD, Associate Deputy Editor.

A collection of POEMs published in AFP is available at http://www.aafp.org/afp/poems.


 

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