CA 125 Relatively Specific for Diagnosing Endometriosis
Am Fam Physician. 2017 Jan 15;95(2):122.
Is serum cancer antigen (CA) 125 an accurate noninvasive test for diagnosing endometriosis in symptomatic women?
For women with symptoms suggestive of endometriosis, serum CA 125 is a relatively specific (93%) and noninvasive test. It can be used to make a presumptive diagnosis in cases for which a medical management approach is being considered without having to perform a (diagnostic standard) laparoscopic procedure to confirm. At minimum, pelvic ultrasonography to assess for other conditions (ovarian cancer or uterine fibroids) that can raise CA 125 levels is needed. CA 125 is not a sensitive test for endometriosis (52%), and therefore not
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