In Patients with Vascular Disease, Treating Sleep Apnea Does Not Reduce the Risk of Cardiovascular Events
Am Fam Physician. 2017 Jan 15;95(2):123.
Does the use of continuous positive airway pressure (CPAP) reduce the likelihood of cardiovascular events?
Compared with usual care, the use of CPAP provides a modest improvement in daytime sleepiness, but does not reduce the likelihood of cardiovascular events, even in a high-risk population. (Level of Evidence = 1b)
Because patients with moderate to severe obstructive sleep apnea have frequent episodes of hypoxia, is it possible that those episodes can trigger cardiovascular events? This physiologically plausible hypothesis has been widely considered, and observational studies have provided it with some support, but it has never been tested in a clinical trial.
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