Single-Dose Dexamethasone an Option for Acute Adult Asthma
Am Fam Physician. 2017 Mar 15;95(6):online.
Is a single dose of dexamethasone as effective as five days of prednisone for acute exacerbations of asthma?
A single dose of 12-mg dexamethasone, which has a longer duration of action than prednisone, is almost as effective as five days of 60-mg prednisone for the prevention of relapse in adults with acute asthma treated in an emergency department. It is a reasonable option for treatment in the emergency department, given its fewer adverse effects. In this study, patients who received the single dose also took placebo for four days. Further research is needed to determine whether patients are comfortable with taking just a single
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