Detrimental Effect of Tight Glucose Control on CV Mortality Persists Over Nine Years
Am Fam Physician. 2017 Mar 15;95(6):online.
What is the long-term effect of intensive blood glucose control in patients with type 2 diabetes mellitus?
The initial Action to Control Cardiovascular Risk in Diabetes (ACCORD) study, which compared standard treatment with intensive control, found that despite good intentions, cardiovascular (CV) and overall mortality are significantly higher when blood glucose levels are lower. This study, which followed patients for an additional five years, found that patients in the intensive treatment group continued to maintain lower A1C levels than patients in the standard care group; they also continued to be at increased risk of death from
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