Repeat Cytology Within Six Months Equals Colposcopy for Younger Women with ASCUS or LSIL
Am Fam Physician. 2017 Apr 1;95(7):455.
Is colposcopy with biopsy better than repeat cytology alone within six months to prevent invasive cervical neoplasia?
Among women 22 to 27 years of age with an index cervical cytology showing abnormal squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL), the incidence of invasive cervical cancer did not differ between repeat cytology within six months or colposcopy with biopsy within six months. For women 28 years or older, there was an increased risk of invasive disease with the repeat cytology approach. Among the younger women, there was an increased incidence of invasive disease using an interval for cytology of seven to 12 months. An initial follow-up approach for the younger group using cytology only within six months would avoid 27% of colposcopic procedures
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This series is coordinated by Sumi Sexton, MD, Associate Deputy Editor.
A collection of POEMs published in AFP is available at http://www.aafp.org/afp/poems.
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