Cover	Photo Quiz	p. 143

	Articles
79	Hepatitis C: Part I. Routine Serologic Testing and Diagnosis LINDA A. MOYER, R.N., ERIC E. MAST, M.D., M.P.H., and MIRIAM J. ALTER, PH.D. The first in a two-part series, this article provides general information on the clinical features and epidemiology of hepatitis C and the tests available for diagnosing this infection.
	Patient information: "Preventing Hepatitis C," p. 91
99	Screening for Genetic Risk of Breast Cancer THOMAS C. ROSENTHAL, M.D., and STIRLING M. PUCK, M.D. Approximately one third of cases of familial breast cancer are due to an inherited mutation in the BRCA1 or BRCA2 gene. The lifetime risk of breast cancer in mutation carriers is above 50 percent.
	Patient information: "Genetic Testing for Breast Cancer Risk: What Does It Mean to Me?," p. 106
113	Poliovirus Vaccine Options RICHARD KENT ZIMMERMAN, M.D., M.P.H., and STEPHEN J. SPANN, M.D. A poliovirus immunization schedule for children should be based on an understanding of the potential risks, costs and benefits of the three options currently available.
	Patient information: "Polio Vaccine," p. 125
131	Snowboarding Injuries CRAIG C. YOUNG, M.D., and MARK W. NIEDFELDT, M.D. Snowboarding, a popular winter sport, involves riding a single board down a ski slope or on a half-pipe snow ramp. Compared with injuries resulting from traditional alpine skiing, snowboarding injuries occur more frequently in the upper extremities and ankles, and less frequently in the knees.
	Patient information: "Tips for Snowboarders," p. 141
143	Surgical Options in the Management of Groin Hernias TIM BAX, M.D., BRETT C. SHEPPARD, M.D., and RICHARD A. CRASS, M.D. Most groin hernias require surgical repair. The many herniorrhaphy techniques can be grouped into four categories: open anterior repair, open posterior repair, tension-free repair with mesh and laparoscopic procedures.
159	Clinical Pharmacology Mirtazapine: A Newer Antidepressant PETER M. HARTMANN, M.D. Mirtazapine exhibits both noradrenergic and serotonergic activity and is effective in the treatment of mild to severe depression. Many physicians consider mirtazapine to be a second- or third-line treatment, for use in patients who have not responded to older antidepressants.

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	Departments
9	Inside AFP
13	Newsletter
17	Quantum Sufficit
21	Clinical Quiz
35	Editorials ACE Inhibitors Therapy: Benefits and Underuse Pros and Cons of Genetic Screening for Breast Cancer
49	Letters to the Editor Sertraline in the Treatment of Obsessive-Compulsive Disorder Maternal Self-Collection of Specimens for GBS Culture
55	CME Calendar
71	Diary from a Week in Practice
163	Photo Quiz
166	Tips from Other Journals
194	Family Practice International
199	Curbside Consultation
203	Special Medical Reports The 1999 Harmonized Immunization Schedule
207	Clinical Briefs
213	Resident and Student Voice
219	Physician's Bookshelf
221	Information for Authors
224	Medical Services
225	Classified Information

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