Cover	649	625

	Articles
575	Clinical Evaluation and Treatment Options for Herniated Lumbar Disc S. CRAIG HUMPHREYS, M.D., and JASON C. ECK, M.S. Most patients with a herniated lumbar disc respond to conservative management. An initial examination to exclude serious pathology is essential, along with monitoring for the development of complications such as neurologic defects, cauda equina syndrome and refractory pain.
	Patient information: "When You Have a Herniated Disc," p. 587
593	Practical Therapeutics Preterm Labor DAVID G. WEISMILLER, M.D., SC.M. Preterm labor is a complex condition with multiple clinical presentations. New clinical and biochemical markers may help physicians predict which women will develop preterm labor, and new management strategies may improve maternal and neonatal outcomes.
605	Incorporating Advance Care Planning into Family Practice PAUL V. AITKEN, JR., M.D., M.P.H. By introducing the subject of advance care planning during a routine office visit, physicians can facilitate a structured discussion of the patient's wishes for end-of-life care.
	Patient information: "Advance Care Planning: Medical Care at the End of Life," p. 613
	Sample advance directive form: p. 617
625	Exfoliative Dermatitis GULIZ KARAKAYLI, M.D., GRANT BECKHAM, M.D., IDA ORENGO, M.D., and TED ROSEN, M.D. In patients with exfoliative dermatitis, most of the skin undergoes an erythematous inflammation that results in massive scaling. A biopsy is usually necessary to make the diagnosis.
635	Clinical Pharmacology Warfarin Therapy: Evolving Strategies in Anticoagulation JON D. HORTON, PHARM.D., and BRUCE M. BUSHWICK, M.D. Warfarin, the most frequently prescribed oral anticoagulant, has a complicated dose-response relationship. Safe and effective administration requires a thorough understanding of the pharmacology of warfarin.

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	Departments
504	Inside AFP
517	Newsletter
521	Quantum Sufficit
525	Clinical Quiz
530	Editorial Advance Directives in Patient Care: If You Ask, They Will Tell You
539	Letters to the Editor Prevention of Malaria and Diarrhea in Travelers
545	Medicine and Society
551	CME Calendar
571	Diary from a Week in Practice
649	Photo Quiz
656	Tips from Other Journals
685	Family Practice International
687	Curbside Consultation
693	Special Medical Reports ACSM/AHA Release Recommendations for Fitness Facilities American College of Chest Physicians Issues Consensus Statement on the Management of Cough
700	Clinical Briefs
707	Physician's Bookshelf
712	Information for Authors
714	Medical Services
715	Classified Information

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