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August 1999 - AFP
Patient Information

Please note: This information was as current as we could make it on the date given above. But medical information is always changing, and some information given here may be out of date. For regularly updated information on a variety of health topics, please visit familydoctor.org, the AAFP patient education Web site.


An article on this topic is available in this issue of AFP.

Peyronie's Disease

What is Peyronie's disease?

Peyronie's disease is a big name for a curve in the penis. (Peyronie's is said this way: pay-rone-ees.) It can be painful at times, most often during sex. In some men, Peyronie's disease is a mild problem without symptoms. Other men with Peyronie's disease may have pain during erection or erections that aren't hard enough for sex.

What causes Peyronie's disease?

Scar tissue under the skin of the penis causes the curve. No one knows why the scar tissue starts. Some men with Peyronie's disease have had a penis injury that causes scar tissue. The scar feels like a ridge or a row of tiny bumps. The scar can keep getting worse during the first few years, making the penis curve more and more. You might notice this more during an erection. After a few years, the scar usually stops getting worse, but it doesn't go away.

What can I do about the curve in my penis?

We can't cure Peyronie's disease. Medicines like Potaba or vitamin E help some men. Potaba is a prescription medicine. Your doctor will tell you about it. If you take vitamin E, don't take more than your doctor tells you. Too much vitamin E won't help your penis. Too much vitamin E or Potaba can hurt your liver. Potaba can also make you nauseous or take away your appetite.

Can surgery help?

Surgery might help men who have very bad pain during sex. Surgery may also be OK for men who can't keep an erection long enough to have sex. During the surgery, a prosthesis (something to make the penis firm) is put in the penis. The prosthesis helps make the penis straighter. It also helps erections last longer.

Can anything else help?

No, although new treatments are being tested. Some of the medicines being tested are put into the scar tissue in shots. So far, the test results don't show any help from these medicines.


This handout provides a general overview on this topic and may not apply to everyone. To find out if this handout applies to you and to get more information on this subject, talk to your family doctor.

Visit familydoctor.org for information on this and many other health-related topics.

Copyright © 1999 by the American Academy of Family Physicians.
Permission is granted to print and photocopy this material for nonprofit educational uses. Written permission is required for all other uses, including electronic uses.


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