• Topic

    Depression and Bipolar Disorders

    This collection features the best content from AFP, as identified by the AFP editors, on depression and bipolar disorder and related issues, including antidepressants, major depressive disorder, mental health, postpartum depression, and psychiatric medications. New research may affect the interpretation and application of this material. Clinical judgment is advised. Note that AFP content published within the past two years is accessible to AAFP members and paid subscribers only.
    Categories

    Treatment

    Editorials and Letters

    Complications and Special Situations

    Patient Education, Self-Care

    Screening and Diagnosis

    Other AFP Content

    Treatment
    Feb 15, 2024 — Brexpiprazole as Adjunctive Therapy for Acute Treatment-Resistant Depression [Medicine by the Numbers]
    Mar 15, 2023 — Management of Major Depression: Guidelines From the VA/DoD [Practice Guidelines]   CME
    Feb 15, 2023 — Pharmacologic Treatment of Depression   CME   FREE   PtEd
    Sep 15, 2022 — Lamotrigine in the Maintenance Treatment of Bipolar Disorder [Cochrane for Clinicians]   CME
    Oct 15, 2021 — Does Light Therapy Decrease Depression in Older Adults? [FPIN's Clinical Inquiries]
    Feb 15, 2021 — Bipolar Disorders: Evaluation and Treatment
    Jan 01, 2021 — Medications for Treatment-Resistant Depression in Adults [Cochrane for Clinicians]
    May 01, 2020 — Antidepressants Plus Benzodiazepines for Adults with Major Depression [Cochrane for Clinicians]
    May 01, 2020 — Lithium for Acute Mania [Cochrane for Clinicians]
    Mar 15, 2020 — Esketamine (Spravato) for Treatment-Resistant Depression [STEPS]
    Mar 01, 2020 — Music Therapy for Depression [Cochrane for Clinicians]
    Feb 01, 2020 — Adverse Events of Pharmacologic Treatments of Major Depression in Older Adults [Implementing AHRQ Effective Health Care Reviews]
    May 15, 2019 — Depression and Anxiety Disorders: Benefits of Exercise, Yoga, and Meditation   PtEd
    Jan 01, 2017 — Extended-Release Bupropion for Preventing Seasonal Affective Disorder in Adults [Cochrane for Clinicians]
    Nov 01, 2015 — Common Questions About Cognitive Behavior Therapy for Psychiatric Disorders   PtEd
    Oct 15, 2015 — Levomilnacipran (Fetzima) for Major Depressive Disorder [STEPS]
    Mar 01, 2015 — Vortioxetine (Brintellix) for the Treatment of Depression [STEPS]
    Apr 01, 2014 — Collaborative Care for Depression and Anxiety [Cochrane for Clinicians]
    Nov 15, 2013 — Second-Generation Antidepressants for Depression in Adults [Implementing AHRQ Effective Health Care Reviews]
    Aug 15, 2013 — Vilazodone (Viibryd) for the Treatment of Depression [STEPS]
    Mar 01, 2012 — Bipolar Disorders: A Review   PtEd
    Nov 01, 2011 — Antidepressants for the Treatment of Insomnia in Patients with Depression [FPIN's Clinical Inquiries]
    May 15, 2011 — Antidepressant Use During Pregnancy [FPIN's Clinical Inquiries]
    Jul 01, 2010 — Effectiveness of Antidepressants Compared with Placebo for Depression in Primary Care [Cochrane for Clinicians]
    Aug 01, 2009 — ACP Guideline on Second-Generation Antidepressants for Depression Treatment [Practice Guidelines]
    Jul 15, 2009 — Treatment-Resistant Depression   Alg
    Aug 01, 2008 — Aripiprazole As Adjunctive Therapy In Patients With Major Depressive Disorder [AFP Journal Club]
    Feb 15, 2008 — Selegiline Transdermal Patch (Emsam) for Major Depressive Disorder [STEPS]
    Editorials and Letters
    Feb 15, 2023 — Comparing Clinical Guidelines for the Management of Major Depressive Disorder [Editorials]   FREE
    Apr 01, 2021 — Preventing Physician Suicide [Editorials]
    Sep 15, 2019 — Can We Prevent Perinatal Depression in the Primary Care Office? [Editorials]
    May 15, 2016 — Opportunities to Detect and Manage Perinatal Depression in Men [Editorials]
    Nov 15, 2014 — Grief and Major Depression—Controversy Over Changes in DSM-5 Diagnostic Criteria [Editorials]
    Aug 01, 2012 — Differentiating Grief and Depression in Patients Who Are Seriously Ill [Editorials]
    Oct 15, 2010 — Translating a Guideline into Practice: The USPSTF Recommendations on Screening for Depression in Adults [Editorials]
    Aug 01, 2007 — Is Genetic Testing for Cytochrome P450 Polymorphisms Ready for Implementation? [Editorials]
    Complications and Special Situations
    Feb 15, 2024 — Exercise for Depression in Older Adults [FPIN's Clinical Inquiries]
    Sep 15, 2023 — Peripartum Depression: Detection and Treatment   CME   PtEd
    Sep 15, 2022 — Collaborative Care for Depression in Older Adults [Lown Right Care]   CME
    Aug 15, 2021 — Physical Activity and the Prevention of Depression [FPIN's Clinical Inquiries]
    Apr 01, 2021 — The Suicidal Patient: Evaluation and Management   PtEd
    Dec 01, 2020 — Seasonal Affective Disorder: Common Questions and Answers
    Nov 01, 2020 — Treatment of Depression in Children and Adolescents [Implementing AHRQ Effective Health Care Reviews]
    Nov 15, 2019 — Depression in Children and Adolescents: Evaluation and Treatment   Alg   PtEd
    Sep 15, 2019 — Interventions to Prevent Perinatal Depression [Putting Prevention Into Practice]
    Sep 15, 2019 — Interventions to Prevent Perinatal Depression: Recommendation Statement [U.S. Preventive Services Task Force]
    Aug 15, 2019 — Cognitive Behavior Therapy for Postpartum Depression [FPIN's Help Desk Answers]
    Jun 15, 2019 — Depression Following Acute Coronary Syndrome Events: Screening and Treatment Guidelines from the AAFP [Practice Guidelines]
    Jun 15, 2019 — Depression Following Acute Coronary Syndrome Events: Screening and Treatment Guidelines from the AAFP [Practice Guidelines]
    Jun 15, 2019 — Depression After ACS Events: AAFP Releases Updated Guidelines [Practice Guidelines]
    Oct 01, 2018 — Depression in Adolescents: AAP Updates Guidelines on Diagnosis and Treatment [Practice Guidelines]
    Oct 01, 2015 — ACOG Releases Recommendations on Screening for Perinatal Depression [Practice Guidelines]
    Jun 01, 2014 — Psychosocial and Psychological Interventions for Preventing Postpartum Depression [Cochrane for Clinicians]
    Dec 15, 2012 — Depression in Children and Adolescents [Clinical Evidence Handbook]
    Aug 01, 2012 — Managing Grief and Depression at the End of Life   PtEd
    Nov 15, 2011 — Clinical Vignettes in Geriatric Depression   PtEd
    Oct 15, 2010 — Postpartum Major Depression   Alg   PtEd
    Patient Education, Self-Care
    Sep 15, 2023 — Depression During and After Pregnancy: When It's More Than the Baby Blues [Information from Your Family Doctor]   FREE
    Feb 15, 2023 — Treating Depression With Medicine [Information from Your Family Doctor]   FREE
    Nov 15, 2019 — Depression in Children and Teens [Information from Your Family Doctor]
    Mar 15, 2012 — Help for People Who Are Thinking About Suicide [Information from Your Family Doctor]   PtEd
    Mar 01, 2012 — Bipolar Disorders [Information from Your Family Doctor]   PtEd
    Nov 15, 2011 — Caring for Older Family Members with Depression [Information from Your Family Doctor]   PtEd
    Oct 15, 2010 — Postpartum Depression [Information from Your Family Doctor]   PtEd
    Mar 15, 2008 — Treating Depression: What You Should Know [Information from Your Family Doctor]   PtEd
    Jan 01, 2007 — Depression in Children and Teens [Information from Your Family Doctor]   PtEd
    Oct 15, 2006 — Depression: What You Should Know [Information from Your Family Doctor]   PtEd
    Jan 01, 2006 — Cognitive Therapy for Depression: What You Should Know [Information from Your Family Doctor]   PtEd
    Sep 15, 2002 — Depression in Women [Information from Your Family Doctor]
    Sep 15, 2002 — Depression [Information from Your Family Doctor]
    Aug 15, 2001 — Depression After Heart Attack-What Should I Know? [Information from Your Family Doctor]   PtEd
    Nov 15, 2000 — What to Do if You Think Your Child Is Depressed [Information from Your Family Doctor]   PtEd
    Mar 01, 2000 — Depression: How Medicine Can Help [Information from Your Family Doctor]   PtEd
    Screening and Diagnosis
    Jan 15, 2024 — Mental Status Examination in Primary Care   CME
    Oct 15, 2018 — Depression: Screening and Diagnosis   PtEd
    Aug 15, 2016 — Screening for Depression in Adults [Putting Prevention Into Practice]
    Aug 15, 2016 — Screening for Depression in Adults: Recommendation Statement [U.S. Preventive Services Task Force]
    Mar 15, 2016 — Screening for Depression in Children and Adolescents: Recommendation Statement [U.S. Preventive Services Task Force]
    Mar 15, 2012 — Evaluation and Treatment of the Suicidal Patient   PtEd
    Jul 15, 2008 — Screening Instruments for Depression [Point-of-Care Guides]   POC
    May 15, 2004 — Routine Screening for Depression, Alcohol Problems, and Domestic Violence [Point-of-Care Guides]   POC
    Other AFP Content
    Nov 01, 2011 — Better Integration of Mental Health Care Improves Depression Screening and Treatment in Primary Care [Graham Center Policy One-Pager]
    Aug 01, 2011 — The Race Against Time: Coping with Anxiety and Depression [Close-ups]

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