Choosing Wisely:

Don’t routinely use seizure prophylaxis in patients following ischemic stroke.

Rationale and Comments: Seizures may complicate the clinical course of patients who have suffered a stroke. However, there is no evidence that using prophylactic antiepileptic drugs prevents seizure occurrence. For patients who suffer a seizure after a stroke, seizure treatment may be required.
Sponsoring Organizations:
  • American Association of Neurological Surgeons and Congress of Neurological Surgeons
  • Sources:
  • Cochrane Database of Systematic Reviews
  • Disciplines:
  • Neurologic
  • References: • Kwan J, Wood E. Antiepileptic drugs for the primary and secondary prevention of seizures after stroke. Cochrane Database of Systematic Reviews 2010, Issue 1. Art. No.: CD005398. doi: 10.1002/14651858.CD005398.pub2.

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