Genetics

This collection features AFP content deemed current by the AFP online medical editor on genetics and related issues, including family medical history, genetic testing, and specific syndromes (fetal alcohol spectrum disorders, fragile X syndrome, Down Syndrome, Klinefelter syndrome, Prader-Willi syndrome, Turner syndrome). New research may affect the interpretation and application of this material. Clinical judgment is advised. Note that AFP content published within the past 12 months is accessible to AAFP members and paid subscribers only.

Last Update: 01/31/2013

Counseling, Testing, and Risk Assessment Family History Pharmacogenetics Specific Syndromes

Editorials and Letters Patient Education, Self-Care Other AFP Content

Counseling, Testing, and Risk Assessment

General

• At-Home Genetic Tests [Curbside Consultation] (02/01/2006)
• Genomic Medicine for Underserved Minority Populations in Family Medicine [Editorials] (08/01/2005)
• The Impact of Genetic Testing on Primary Care: Where's the Beef? [Medicine and Society] (02/15/2000)
• Genetic Testing for Disease Susceptibility: Social, Ethical and Legal Issues for Family Physicians [Medicine and Society] (09/01/1999)

Specific Conditions

• Hereditary Hemochromatosis (02/01/2013)
• ACOG Guidelines for Managing Hereditary Breast and Ovarian Cancer Syndrome [Practice Guidelines] (12/15/2009)
• Cancer Genetic Risk Assessment for Individuals at Risk of Familial Breast Cancer [Cochrane for Clinicians] (02/15/2008)
• Screening for Hemochromatosis: Recommendation Statement [U.S. Preventive Services Task Force] (06/01/2007)
• Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility [Putting Prevention into Practice] (11/15/2006)
• Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility: Recommendation Statement [U.S. Preventive Services Task Force] (03/01/2006)

Family History

• Family History: The Three-Generation Pedigree (08/01/2005)
• Personalizing Prevention: The U.S. Surgeon General's Family History Initiative [Editorials] (01/01/2005)

Pharmacogenetics

• Genetic Factors In Drug Metabolism (06/01/2008)
• Pharmacogenentics: Using DNA to Optimize Drug Therapy (10/15/2007)
• The Effect of Cytochrome P450 Metabolism on Drug Response, Interactions, and Adverse Effects (08/01/2007)

Specific Syndromes

• When to Suspect a Genetic Syndrome (11/01/2012)
• Turner Syndrome: Diagnosis and Management (08/01/2007)
• Klinefelter Syndrome (12/01/2005)
• Prader-Willi Syndrome (09/01/2005)
• Fetal Alcohol Spectrum Disorders (07/15/2005)
• Diagnosis and Managment of Fragile X Syndrome (07/01/2005)
• Down Syndrome: Prenatal Risk Assessment and Diagnosis (08/15/2000)

Editorials and Letters

• The CDC's EGAPP Initiative: Evaluating the Clinical Evidence for Genetic Tests [Editorials] (12/01/2009)
• Is Genetic Testing for Cytochrome P450 Polymorphisms Ready for Implementation? [Editorials] (08/01/2007)
• Integrating Genetic Counseling into Family Medicine [Editorials] (12/15/2005)
• Genetic Testing: When to Test, When to Refer [Editorials] (07/01/2005)
• Genomics and the Family Physician: Realizing the Potential [Editorials] (11/01/2004)
• Family History and Genetic Testing for Cancer Risk [Letters to the Editor] (04/15/2010)
• Genetic Counseling in Preconception Health Care [Letters to the Editor] (12/15/2002)

Patient Education, Self-Care

• Prenatal Genetic Screening Tests (01/15/2009)

From FamilyDoctor.org

AAFP's Patient Education Resource

• Genetic Testing: What You Should Know

Other AFP Content