AFP DEPARTMENT COLLECTION

POEMs

POEMs (Patient-Oriented Evidence that Matters) are summaries of research that is relevant to physicians and their patients and meet three criteria: address a question that primary care physicians face in day-to-day practice; measure outcomes important to physicians and patients, including symptoms, morbidity, quality of life, and mortality; and have the potential to change the way physicians practice.

Sep 15, 2017 Issue
Steroid Treatment Adds No Benefit to Antihistamines for Acute Hives
The combination approach of steroids and antihista-mines offers no added benefit to antihistamines alone for the treatment of simple urticaria.


Sep 15, 2017 Issue
Corticosteroid Injections Ineffective for Knee Osteoarthritis
This well-done study found that regular three-month intra-articular injections of triamcinolone for two years resulted in no significant difference in pain and function assessments compared with saline. However, a significant increase in cartilage loss and damage did occur in patients receiving corticosteroids compared with saline.


Sep 15, 2017 Issue
No Benefit with Addition of TMP/SMX to Cephalexin for Nonpurulent Cellulitis
Compared with cephalexin alone, covering for methicillin-resistant Staphylococcus aureus (MRSA) and streptococci with cephalexin plus TMP/SMX does not improve rates of clinical cure when treating nonpurulent cellulitis. However, a trend favoring the combination regimen was found in a modified intention-to-treat population in this study, so further research may be required.


Sep 1, 2017 Issue
Combination of Resistance and Aerobic Exercise Best for Older Persons with Obesity
In older patients with obesity embarking on a program to improve their health, weight loss accompanied by resistance training and aerobic training resulted in the biggest gains in functional status and physical performance.


Aug 15, 2017 Issue
No Added Benefit with Higher Doses of Ketorolac for Treatment of Acute Pain in the Emergency Department
A 10-mg dose of ketorolac is as effective as higher doses for the short-term treatment of acute pain for patients in the emergency department.


Aug 15, 2017 Issue
No Increased Risk of ASD, ADHD, or SGA with First-Trimester Antidepressant Use
This study found that maternal antidepressant use during the first trimester of pregnancy is associated with an increased risk of preterm birth, but not SGA, ASD, or ADHD. Another study in the same issue also reported no increased risk of ASD with in utero exposure to selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors.


Aug 15, 2017 Issue
Dexamethasone May Reduce Sore Throat Symptoms in Adults at 48 Hours
A single dose of oral dexamethasone is no more effective than placebo in resolving acute sore throat symptoms at 24 hours in adults who do not receive immediate antibiotic therapy. However, among a multitude of exploratory secondary outcomes, the authors found that, compared with placebo, dexamethasone increased the proportion of patients with symptom resolution at 48 hours.


Aug 15, 2017 Issue
Pregabalin Does Not Decrease the Pain of Sciatica
Pregabalin does not relieve pain in patients with sciatica.


Jul 15, 2017 Issue
Niacin Does Not Decrease Mortality in Patients with Coronary Artery Disease or Low HDL
We are now flush with data about the effects of niacin in patients with elevated cholesterol levels. Despite its ability to raise high-density lipoprotein (HDL) serum cholesterol levels, it does not add additional mortality or morbidity benefit to statin treatment. Patients with diabetes mellitus may also experience worse blood glucose control, as well as other niacin-related adverse effects.


Jul 15, 2017 Issue
High False-Positive Rate with Lung Cancer Screening
If you are thinking about adding lung cancer screening to your delivery of preventive care, be sure to prepare patients. They are likely to receive a positive result, most of the positive results will not be lung cancer, and one in four patients will require additional tracking (i.e., follow-up scans).


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