AFP DEPARTMENT COLLECTION

Medicine by the Numbers

From The NNT Group, these provide short, concise, evidence-based ratings of therapies, diagnostic tests, and risk assessments commonly used in family medicine. These rating are based on patient-important benefits and harms.

Jul 1, 2017 Issue
Tenofovir for Prevention of HIV Infection


Jun 1, 2017 Issue
Efficacy of Direct-Acting Antivirals Compared with Older Agents for Hepatitis C
Although they help patients achieve sustained viralogic response, expensive direct-acting antivirals have yet to show that they can succeed in meeting top-priority treatment goals.


May 1, 2017 Issue
Oral NSAIDs for Perineal Pain in the Early Postpartum Period
Oral nonsteroidal anti-inflammatory drugs were able to adequately relieve perineal pain for many postpartum women at four hours and longer.


Apr 1, 2017 Issue
Vitamin E in Pregnancy
Vitamin E supplementation in pregnant women does not show any benefit among the most patient-important outcomes.


Mar 1, 2017 Issue
Buprenorphine Maintenance vs. Placebo for Opioid Dependence
Buprenorphine causes lower physical dependence, milder withdrawal symptoms, and is less likely to cause an overdose than methadone in the treatment of opioid dependence.


Feb 1, 2017 Issue
Antiepileptic Drugs After First Unprovoked Seizure
The decision to start an antiepileptic drug after a first unprovoked seizure has long been a clinically challenging one.


Jan 1, 2017 Issue
Alpha-adrenergic Agonists for the Management of Opioid Withdrawal
Alpha-adrenergic agonists were more efficacious than placebo in the management of opioid withdrawal, but are best reserved as an alternative to methadone.


Dec 1, 2016 Issue
Aripiprazole vs. Placebo or Haloperidol for Schizophrenia
Aripiprazole was shown to have one major benefit over placebo, but favorable outcomes with haloperidol throw its effectiveness into question. Are the differences merely anomalies?


Nov 1, 2016 Issue
Valproate for Adult Migraine Prophylaxis
Evidence supports current guideline recommendations on the use of valproate medications to prevent migraine.


Oct 1, 2016 Issue
Rivaroxaban vs. Warfarin for Anticoagulation in Patients with Atrial Fibrillation Undergoing Ablation and Cardioversion
Studies showed that 433 patients needed to be treated with rivaroxaban to prevent one stroke and 629 patients needed to be treated with rivaroxaban to prevent one thromboembolic event. Read more.


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