AFP DEPARTMENT COLLECTION

FPIN's Clinical Inquiries

Clinical Inquiries from the Family Physicians Inquiries Network (FPIN) provide short, concise, evidence-based answers to clinical questions common in family medicine. The answers include a summary of the evidence and commentary that puts the answers into perspective.

Apr 15, 2017 Issue
Iron Deficiency in Heart Failure
Treatment of iron deficiency in patients with heart failure using intravenous iron improves function, fatigue, and quality of life, and decreases risk of hospitalizations compared with placebo.


Jan 15, 2017 Issue
Giant Cell Arteritis: Biopsy After Corticosteroid Initiation
Corticosteroid therapy in patients with suspected giant cell arteritis should not degrade the accuracy of temporal artery biopsy if the biopsy is performed within four weeks of corticosteroid initiation. Temporal artery biopsy can be performed up to four weeks after starting high-dose corticosteroid therapy.


Oct 15, 2016 Issue
ACE Inhibitors or ARBs to Prevent CKD in Patients with Microalbuminuria
ACE inhibitors reduce the risk of progression to macroalbuminuria in normotensive patients with microalbuminuria and type 1 diabetes mellitus.


Jul 1, 2016 Issue
Procalcitonin-Guided Antibiotic Therapy for Acute Respiratory Infections
A procalcitonin-guided antibiotic therapy algorithm should be used to decrease antibiotic use in adults with acute respiratory infections. The use of a procalcitonin-guided therapy algorithm reduces antibiotic use by 3.47 days without increasing morbidity or mortality in adults with acute respiratory infections.


Oct 1, 2015 Issue
Risk of Gout with the Use of Thiazide Diuretics
Thiazide diuretics may be used in most patients with hypertension who have only minimally increased risk of gout.


Sep 15, 2015 Issue
Atopic Eczema and Early Introduction of Solid Foods
In most children, solid foods may be introduced before four to six months of age without increasing the risk of atopic eczema.


Aug 1, 2015 Issue
Micronutrient Supplementation During Pregnancy
A multimicronutrient supplement is an oral tablet containing the recommended daily allowance of several vitamins and minerals. The World Health Organization does not recommend multimicronutrient supplementation because of the potential for increased neonatal mortality in some situations.


Jun 1, 2015 Issue
Management of Acute Achilles Tendon Rupture
There are no clear evidence-based criteria to decide which patients should undergo operative vs. nonoperative management of acute Achilles tendon rupture.


May 1, 2015 Issue
Treatments for Sciatica
Surgical diskectomy can be offered to patients with refractory sciatica, but there is only modest, short-term improvement in leg pain and disability scores. Epidural steroid injections may be offered to patients with sciatica of more than six months' duration.


Apr 1, 2015 Issue
Exercise and Pregnancy Loss
Regular exercise for up to seven or more hours per week (including low-intensity and high-intensity aerobics, jogging, cycling, and swimming) is not associated with increased rates of miscarriage in the first to mid-second trimesters. Patients may continue bending and lifting at work, because these activities are not associated with increased first-trimester miscarriage rates.


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