FPIN's Clinical Inquiries

Clinical Inquiries from the Family Practice Inquiries Network (FPIN) provide short, concise, evidence-based answers to clinical questions common in family medicine. The answers include a summary of the evidence and commentary that puts the answers into perspective.

Sep 15, 2011 Issue
Effective Therapies for Intermittent Claudication
Supervised exercise programs are recommended to produce clinically significant improvements in walking distance in patients with stable intermittent claudication.

Sep 1, 2011 Issue
Exercise for the Treatment of Knee Osteoarthritis
Regular exercise reduces osteoarthritic knee pain and improves functioning.

Aug 15, 2011 Issue
Preventing Acute Mountain Sickness
Gradual ascent is the most effective method for preventing acute mountain sickness.

Aug 1, 2011 Issue
Evaluation of Ovarian Cysts
Initial evaluation of an ovarian cyst is largely determined by its characteristics on ultrasonography, in addition to the presence of symptoms, laboratory evaluation, and patient history. Women with an ovarian cyst, but with no symptoms, family or personal history of cancer (e.g., ovarian, breast, colorectal), physical or laboratory evidence suggestive of infection, pregnancy, or systemic illness, are considered at low risk of ovarian cancer and may be followed with serial ultrasonography.

Jul 15, 2011 Issue
Antibiotic Prophylaxis to Prevent Recurrent UTI in Children
Antibiotic prophylaxis to prevent recurrent UTI may be considered in infants and children with or without vesicoureteral reflux (VUR) after a first UTI.

Jul 1, 2011 Issue
Hormone Therapy for Postmenopausal Women with Urinary Incontinence
Postmenopausal women should not receive oral hormone therapy for treatment of urinary incontinence.

Jun 15, 2011 Issue
Treatment of Recurrent Vulvovaginal Candidiasis
A six-month treatment regimen with an antifungal agent decreases the recurrence of vulvovaginal candidiasis.

Jun 1, 2011 Issue
Brain Natriuretic Peptide for Ruling Out Heart Failure
A BNP level less than 100 pg per mL (100 ng per L) can rule out heart failure.

May 15, 2011 Issue
Antidepressant Use During Pregnancy
There are no studies that have shown any antidepressant to be absolutely safe for use during any stage of pregnancy. The use of selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs) during pregnancy does not increase the risk of congenital malformations or miscarriage.

May 1, 2011 Issue
Clinical Indicators of Obstructive Sleep Apnea
Clinical indicators (e.g., sex, snoring severity, history of apnea, age, menopausal status, waist-to-hip ratio, body habitus) can predict OSA as diagnosed using overnight polysomnography or sleep study.

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