AFP Journal Club

Three presenters review an interesting journal article on topics that affect family physicians and give their opinions about the clinical value of the studies.

Jul 15, 2009 Issue
Honey as a Treatment for Cough in Children
Is honey an effective treatment for cough in children? Although this study failed to provide convincing evidence of effectiveness, honey may be a safe alternative to soothe cough in children older than one year.

May 15, 2009 Issue
Sample Medications and Overall Prescription Costs
What are the effects of providing sample medications to patients? It increases prescription costs and causes physicians to use second-line choices.

Mar 15, 2009 Issue
Acyclovir or Steroids as Pharmacologic Treatment of Bell Palsy
Does acyclovir or steroids speed recovery in adults with Bell palsy? This study suggests that it is reasonable to start prednisolone in some cases, but physicians should not forget about practical considerations, such as lubricant eye drops, pain management, and chewing instruction. Acyclovir was of no benefit

Dec 1, 2008 Issue
Is Prasugrel More Effective Than Clopidogrel in Patients with Acute Coronary Syndrome Scheduled for PCI?
Is prasugrel better than clopidogrel in patients with acute coronary syndrome who are scheduled for percutaneous coronary intervention? This study is misleading, and current practice should not change based on its results.

Oct 1, 2008 Issue
Does Limiting Interruptions During Cardiac Resuscitation Improve Outcomes
Does the ACLS recommendation to limit interruptions during cardiac resuscitation improve outcomes for patients with cardiac arrest? It is a reasonable recommendation, but success rates in this study may be too good to believe.

Sep 1, 2008 Issue
The Role of Chest CT in Diagnosing Pulmonary Embolism
How good is chest CT at identifying pulmonary embolism? It might have higher false-positive and false-negative rates than previously thought.

Aug 1, 2008 Issue
Aripiprazole as Adjunctive Therapy in Patients with Major Depressive Disorder
Does augmentation with aripiprazole help patients with major depressive disorder who have not responded to initial therapy? Adding aripiprazole to SSRIs or SNRIs did not significantly improve depression in this study. However, this study did not compare the study drug with a real-world scenario.

Jul 1, 2008 Issue
Inhaled Steroid Use and Asthma Control in Patients with Mild Persistent Asthma
Can patients with mild persistent asthma safely decrease or eliminate inhaled steroids? The results of these studies may not be generalizable to the average primary care patient. Patients should be appropriately classified and treated using 2007 National Asthma Education and Prevention Program guidelines.

Jun 1, 2008 Issue
Is Unfractionated Heparin Equivalent to Low-Molecular-Weight Heparin for Venous Thromboembolism?
Is weight-based unfractionated heparin as good as weight-based low-molecular-weight heparin for outpatient treatment of venous thromboembolism? Even though this study was underpowered to prove equivalence, treatment with subcutaneous unfractionated heparin is a viable option.

May 1, 2008 Issue
Albuterol vs. Levalbuterol for Asthma Treatment in Children
For children with acute asthma exacerbations, is levalbuterol better than albuterol? There is no difference between the medications in effectiveness or side effects.

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