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Osteoarthritis, gout, and trauma are the most common causes of acute monoarthritis. Review the typical history and examination findings for these and other etiologies. If infection is suspected, arthrocentesis should be performed for synovial fluid analysis.
Many conditions can cause joint pain. Diagnosis requires distinguishing between inflammatory and noninflammatory arthritis, as well as recognizing nonarticular conditions. Learn the common symptoms and signs of the possible etiologies of joint pain.
A man presented with severe pain and swelling in his knees and wrists that affected his ability to walk, and a rash on his thighs, knees, hands, and lower back.
Methotrexate monotherapy demonstrated statistically significant and clinically relevant improvement of symptoms and physical function compared with placebo at 12 to 52 weeks. Multiple adverse effects were reported with methotrexate use, and patients were twice as likely to discontinue methotrexate therapy when compared with placebo.
Find out whether newer medications are any more effective than older ones, and the latest evidence on dietary modifications and pharmacologic therapy for prevention of recurrent gout.
In this study, physical therapy was no more effective than sham therapy in reducing pain and improving function in adults with hip osteoarthritis.
Compared with normal saline or hyaluronic acid, multiple intra-articular injections of platelet-rich plasma significantly improved knee function but did not reduce perceived pain or improve patient satisfaction in adults with symptomatic knee osteoarthritis.
For middle-aged or older adults with osteoarthritis and a meniscal tear, there seem to be no significant differences between arthroscopic surgery plus PT and PT alone. A subset of patients who do not respond well to PT alone will eventually have surgery, but if they cross over to surgery within six ...
Vitamin D supplementation at a dose targeted to reach a 25-hydroxyvitamin D plasma level greater than 36 ng per mL for two years did not reduce symptomatic knee pain in adults with osteoarthritis.
Hyaluronic acid injection does not improve pain in patients with knee osteoarthritis but may result in serious adverse effects.