ITEMS IN AFP WITH KEYWORD:
Gastroesophageal Reflux Disease
Review the clinical features that differentiate reflux from GERD. Learn the warning signs that require further evaluation and the recommended strategies for conservative management and pharmacotherapy.
Sep 1, 2015 Issue
Pharmacologic Therapy for Gastroesophageal Reflux Disease in Children [Cochrane for Clinicians]
Among infants younger than 12 months diagnosed with GERD, weak evidence supports the use of proton pump inhibitors (PPIs) and histamine H2 antagonists. Among children 12 months and older, studies have shown moderate benefit from PPIs and weak benefit from H2 antagonists for providing symptomatic rel...
Find out which medications are most effective, when surgery may be indicated, and which patients should be screened for Barrett esophagus and Helicobacter pylori infection, and learn about adverse effects of medications.
The American Academy of Pediatrics (AAP) has published a guideline on the management of gastroesophageal reflux (GER) in children based on recommendations from the North American and European Societies for Pediatric Gastroenterology, Hepatology, and Nutrition. It is important to determine whether th...
Data suggest that upper endoscopy in patients with symptoms of gastroesophageal reflux disease (GERD) is useful only in certain situations. To help physicians avoid the overuse of interventions that have little effect on health outcomes, the American College of Physicians (ACP) recently published re...
What are the effectiveness, benefits, and harms of therapies used to address symptoms and prevent adverse long-term outcomes in adults with gastroesophageal reflux disease (GERD)?
May 15, 2011 Issue
Should We Screen Patients for Barrett's Esophagus? Yes: Men with Long-standing Reflux Symptoms Should Be Screened with Endoscopy [Editorials: Controversies in Family Medicine]
Although screening and surveillance for Barrett's esophagus is controversial, the latest evidence supports this approach to decrease morbidity and mortality. Carefully evaluating patients with reflux symptoms and stratifying them based on known risk factors has the potential to result in decreased c...
May 15, 2011 Issue
Should We Screen Patients for Barrett's Esophagus? No: The Case Against Screening [Editorials: Controversies in Family Medicine]
Although there is enthusiasm in some groups for screening patients for Barrett's esophagus, with the goal of reducing death from esophageal adenocarcinoma, review of the evidence does not show sufficient benefit to recommend such a program.
Aug 1, 2010 Issue
Medical Management vs. Surgery for Gastroesophageal Reflux Disease [Cochrane for Clinicians]
At one to three years, adults with GERD who were treated with laparoscopic fundoplication had more improvement in overall and GERD-specific quality of life scores and less exposure to acid in the lower esophagus compared with patients who use proton pump inhibitors (PPIs) and histamine H2 blockers. ...
Diagnosis of GERD may be clinical (presentation with typical symptoms, such as heartburn); physiologic (evidence of abnormal pH levels in the distal esophagus); anatomic (evidence of esophagitis on endoscopy); or functional (clinical response to antacid medications). However, the correlation between these diagnostic approaches is relatively poor.