ITEMS IN AFP WITH KEYWORD:

Stroke

Jul 15, 2014 Issue
New Anticoagulants vs. Warfarin in Atrial Fibrillation: No Clear Winner [POEMs]

In this meta-analysis, newer anticoagulants appear to be slightly more effective than warfarin in the short term (two years) in preventing strokes of all kinds in patients with atrial fibrillation. However, they are no more effective than warfarin in preventing ischemic strokes, and they cause more ...


Apr 15, 2014 Issue
Apixaban (Eliquis) for Stroke Prevention in Atrial Fibrillation [STEPS]

Apixaban is at least as effective as aspirin or warfarin for preventing strokes in high-risk patients with nonvalvular atrial fibrillation, especially those who cannot or will not take warfarin. It is slightly less likely to cause major bleeding and may have better compliance because it does not req...


Jan 1, 2014 Issue
Clopidogrel Plus 21 Days of Aspirin Is Superior to Aspirin Alone Within First 24 Hours of TIA or Minor Stroke [POEMs]

Patients with minor stroke (National Institutes of Health [NIH] Stroke Scale score ≤ 3) or TIA have a decreased risk of recurrent stroke if given aspirin plus clopidogrel vs. aspirin alone if started within 24 hours of the onset of symptoms. There was no significant increase in the risk of bleeding ...


Jul 1, 2013 Issue
Endovascular Therapies Do Not Improve Outcomes in Acute Stroke [POEMs]

Endovascular therapies (local delivery of t-PA, extracting the thrombus, or stenting) do not improve outcomes when added to intravenous t-PA alone.


May 15, 2013 Issue
AHA/ASA Publish Advisory on Oral Antithrombotics for Stroke Prevention in Nonvalvular Artial Fibrillation [Practice Guidelines]

New antithrombotics provide alternatives to warfarin, and may lower the threshold for thromboembolic risk for initiating therapy in patients with atrial fibrillation. This advisory summarizes existing American Heart Association/American Stroke Association (AHA/ASA) recommendations on antithrombotics...


Dec 1, 2012 Issue
Insulin for Glycemic Control in Acute Ischemic Stroke [Cochrane for Clinicians]

Administering insulin to maintain glycemic control does not improve the rates of mortality or dependency, or the final neurologic outcome after an acute ischemic stroke. Additionally, in randomized controlled trials, patients in the intervention groups (those under tight glycemic control) had a 25-fold higher incidence of symptomatic hypoglycemia.


Oct 15, 2012 Issue
Rivaroxaban (Xarelto) for Prevention of Thromboembolic Events [STEPS]

In patients at high risk of stroke because of nonvalvular atrial fibrillation, rivaroxaban is as safe and effective as warfarin. However, it should not be used in patients at risk of stroke for reasons other than nonvalvular atrial fibrillation until research shows its relative safety and effectiveness.


Sep 15, 2012 Issue
Transient Ischemic Attack: Part I. Diagnosis and Evaluation [Article]

Transient ischemic attack is defined as transient neurologic symptoms without evidence of acute infarction. It is a common and important risk factor for future stroke, but is greatly underreported. Common symptoms are sudden and transient, and include unilateral paresis, speech disturbance, and mono...


Sep 15, 2012 Issue
Transient Ischemic Attack: Part II. Risk Factor Modification and Treatment [Article]

Interventions following a transient ischemic attack are aimed at preventing a future episode or stroke. Hypertension, current smoking, obesity, physical inactivity, diabetes mellitus, and dyslipidemia are all well-known risk factors, and controlling these factors can have dramatic effects on transie...


Dec 15, 2011 Issue
Dabigatran (Pradaxa) for Prevention of Stroke in Atrial Fibrillation [STEPS]

Dabigatran is superior to warfarin for stroke prevention in patients with atrial fibrillation, with similar rates of major bleeding. Because it does not require laboratory monitoring, dabigatran therapy is less complicated than warfarin therapy, but it costs significantly more.


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