ITEMS IN AFP WITH KEYWORD:
Regular yoga improves quality of life as measured on the Asthma Quality of Life Questionnaire (mean difference = 0.57 units on a seven-point scale; 95% confidence interval [CI], 0.37 to 0.77); improves asthma symptoms (standardized mean difference = 0.37; 95% CI, 0.09 to 0.65); and reduces medicatio...
This study found that current asthma was ruled out after repeated testing in one-third of adults with physician-diagnosed asthma. Patients ruled out for current asthma were less likely to be using asthma medications or daily controlling medications and less likely to have undergone testing for airflow limitation at the time of initial diagnosis.
A single dose of 12-mg dexamethasone, which has a longer duration of action than prednisone, is almost as effective as five days of 60-mg prednisone for the prevention of relapse in adults with acute asthma treated in an emergency department.
Therapeutic agents used in the management of chronic asthma aim to prevent symptoms by controlling airway inflammation and hyperreactivity. Medication regimens are organized in stepwise approaches based on patient age. Data regarding the safety and efficacy of popular complementary and alternative asthma treatments are largely unavailable.
The combination of fluticasone and salmeterol (Advair), with the steroid dose adjusted for disease severity, reduces the number of severe asthma exacerbations more than fluticasone (Flovent) alone (number needed to treat [NNT] = 50 over 26 weeks), with no difference in terms of potential harms, such as intubation or asthma-related death.
In addition to usual beta-agonist treatment, a single dose of oral dexamethasone is as effective as three days of prednisolone (with less vomiting) in decreasing respiratory symptoms without increasing hospitalizations, follow-up visits, and days lost from school. Additional treatment with a steroid...
Intermittent inhaled corticosteroid therapy reduces the risk of asthma exacerbations in children and adults with mild persistent asthma. Intermittent use appears to be safe in these patients.
Apr 1, 2016 Issue
Leukotriene Receptor Antagonists in the Treatment of Acute Asthma [Medicine by the Numbers]
Studies show there were no patient-important benefits and no hospital admissions were prevented. Want to know more?
Oct 1, 2014 Issue
Safety of Long-Acting Beta Agonists in Adults with Asthma [Cochrane for Clinicians]
LABAs appear to be safe when used with inhaled corticosteroids. LABA monotherapy is associated with an increase in asthma-related mortality and nonfatal serious adverse events, but not in all-cause mortality.
Mar 15, 2014 Issue
PPIs, Childhood Asthma, and the Problem of Therapeutic Creep [AFP Journal Club]
The use of a therapy in patients one would intuitively think might benefit, but in whom no benefit has been documented, is called therapeutic creep. The use of proton pump inhibitors for poorly controlled asthma is an example of this phenomenon.