Items in AFP with MESH term: Biopsy

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Cutaneous Manifestation of a Systemic Disease - Photo Quiz

Tongue Bump - Photo Quiz

Should Risk Factors for Breast Cancer Influence Evaluation of Breast Abnormalities? - Editorials

The 2001 ASCCP Management Guidelines for Cervical Cytology - Editorials

An Elderly Woman with a Non-healing Ulcer - Photo Quiz

Multiple Erythematous Plaques of the Trunk - Photo Quiz

"Wood-Grain" Skin - Photo Quiz

Soft Tissue Mass over Right Brow - Photo Quiz

Punch Biopsy of the Skin - Article

ABSTRACT: Skin biopsy is one of the most important diagnostic tests for skin disorders. Punch biopsy is considered the primary technique for obtaining diagnostic full-thickness skin specimens. It requires basic general surgical and suture-tying skills and is easy to learn. The technique involves the use of a circular blade that is rotated down through the epidermis and dermis, and into the subcutaneous fat, yielding a 3- to 4-mm cylindrical core of tissue sample. Stretching the skin perpendicular to the lines of least skin tension before incision results in an elliptical-shaped wound, allowing for easier closure by a single suture. Once the specimen is obtained, caution must be used in handling it to avoid crush artifact. Punch biopsies are useful in the work-up of cutaneous neoplasms, pigmented lesions, inflammatory lesions and chronic skin disorders. Properly administered local anesthesia usually makes this a painless procedure.

Fusiform Excision - Article

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