Items in AFP with MESH term: Predictive Value of Tests

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A1C Testing in the Diagnosis of Diabetes Mellitus - FPIN's Clinical Inquiries


Predicting Short-term Risk of Stroke After TIA - Point-of-Care Guides


Diabetes Mellitus: Diagnosis and Screening - Article

ABSTRACT: Based on etiology, diabetes is classified as type 1 diabetes mellitus, type 2 diabetes mellitus, latent autoimmune diabetes, maturity-onset diabetes of youth, and miscellaneous causes. The diagnosis is based on measurement of A1C level, fasting or random blood glucose level, or oral glucose tolerance testing. Although there are conflicting guidelines, most agree that patients with hypertension or hyperlipidemia should be screened for diabetes. Diabetes risk calculators have a high negative predictive value and help define patients who are unlikely to have diabetes. Tests that may help establish the type of diabetes or the continued need for insulin include those reflective of beta cell function, such as C peptide levels, and markers of immune-mediated beta cell destruction (e.g., autoantibodies to islet cells, insulin, glutamic acid decarboxylase, tyrosine phosphatase [IA-2a and IA-2ß]). Antibody testing is limited by availability, cost, and predictive value.


Global Risk of Coronary Heart Disease: Assessment and Application - Article

ABSTRACT: Coronary heart disease is the most common cause of death in the United States. The conventional risk factor approach to primary prevention excludes many patients who could benefit from preventive therapies. A global risk approach allows more accurate estimates of risk to guide clinical primary prevention efforts. Global risk of coronary heart disease is a calculation of the absolute risk of having a coronary heart disease event (e.g., death, myocardial infarction) over a specified period. It is based on an empiric equation that combines major risk factors, such as blood pressure and cholesterol levels. When physicians know a patient’s global risk of coronary heart disease, they are more likely to prescribe risk-reducing therapies such as antihypertensives, statins, and aspirin. In addition, patients who know their risk level are more likely to initiate risk-reducing therapies. Many tools are available to estimate global risk, including several Web-based calculators. In the United States, tools based on the Framingham Heart Study are recommended.


Predicting the Risk of Bleeding in Patients Taking Warfarin - Point-of-Care Guides


Screening for Osteoporosis: Recommendation Statement - U.S. Preventive Services Task Force


Screening for Osteoporosis - Putting Prevention into Practice


Brain Natriuretic Peptide for Ruling Out Heart Failure - FPIN's Clinical Inquiries


Should the Target A1C Level Be Less Than 7 Percent? Yes: This Should Be the Target for Most Patients - Editorials


Prevention of Falls in Community-Dwelling Older Adults: Recommendation Statement - U.S. Preventive Services Task Force


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