Clinical Care & Research http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research.html en-us Copyright 2009 American Academy of Family Physicians Demand Outpacing Supply of H1N1, Seasonal Flu Vaccines http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091118harvard-h1n1-poll.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091118harvard-h1n1-poll.html The overwhelming majority of Americans who have tried to get vaccinated against the novel influenza A (H1N1) virus have been unable to do so, according to a recent poll from the Harvard University School of Public Health, Boston. Meanwhile, the CDC said on Nov. 9 that nearly 80 percent of seasonal flu vaccine already has been distributed to vaccine providers, and a surge in uptake may leave supplies short of demand. ann@aafp.org Wed, 18 Nov 2009 16:55:00 CST Clinical Care & Research One Dose of H1N1 Vaccine Immunogenic in High Percentage of Pregnant Women http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091104preg-wmn-trial.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091104preg-wmn-trial.html Pregnant women, who have been among the most vulnerable to serious health problems associated with the novel influenza A (H1N1) virus, can take some comfort in the protection offered by the H1N1 vaccine. Initial results from an ongoing clinical trial sponsored by the NIH's National Institute of Allergy and Infectious Diseases, or NIAID, showed that healthy pregnant women mount a robust immune response after a single dose of the vaccine. ann@aafp.org Wed, 04 Nov 2009 16:25:00 CST Clinical Care & Research FDA Working to Revise Prescribing Information for Diabetes Medications http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091104fdarevisions.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091104fdarevisions.html The FDA is revising the prescribing information for the injectable diabetes medication exenatide and the oral diabetes drug sitagliptin phosphate following reports of renal problems associated with exenatide use, as well as reports linking sitagliptin use with pancreatitis. ann@aafp.org Wed, 04 Nov 2009 16:55:00 CST Clinical Care & Research H1N1 Vaccine Production, Availability Increasing Slowly http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091030h1n1availability.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091030h1n1availability.html Vaccine manufacturers are expected to fall well short of having 40 million doses of novel influenza A (H1N1) vaccine available by the end of October, but HHS Secretary Kathleen Sebelius recently told the Senate's Homeland Security and Governmental Affairs Committee that the target likely will be reached in early November. At an Oct. 21 hearing to update the public on federal efforts to manage the spread of H1N1 influenza, Sebelius said problems with vaccine production yield have been resolved and production is increasing. dmitchell@aafp.org Fri, 30 Oct 2009 16:35:00 CDT Clinical Care & Research ACIP Supports 'Permissive Use,' But Not Routine Use, of Gardasil in Males http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091027acip-hpv-vacc.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091027acip-hpv-vacc.html The CDC's Advisory Committee on Immunization Practices, or ACIP, has recommended against the routine use of quadrivalent human papillomavirus, or HPV, vaccine to prevent genital warts in boys and young men. Instead, the committee voted during its Oct. 21-22 meeting in Atlanta to support the "permissive use" of Gardasil, Merck & Co. Inc.'s quadrivalent HPV vaccine, leaving decisions on whether to immunize males ages 9-26 years who request the vaccine up to their health care professionals. dmitchell@aafp.org Tue, 27 Oct 2009 17:15:00 CDT Clinical Care & Research CDC Survey Shows Gains in Overall Adolescent Vaccination Rates for 2008 http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091021teen-vaccs.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091021teen-vaccs.html Vaccination rates among the nation's adolescents showed significant increases in 2008 compared with the previous year, but coverage still is less than 50 percent for three vaccines specifically recommended for preteens, according to recent survey findings from the CDC. ann@aafp.org Wed, 21 Oct 2009 14:55:00 CDT Clinical Care & Research FDA Approves Gardasil to Prevent Genital Warts in Males http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091019hpvmen-bivalgsk.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091019hpvmen-bivalgsk.html The FDA has expanded its approval of Merck & Co. Inc.'s quadrivalent human papillomavirus, or HPV, vaccine, which is marketed as Gardasil, to include use of the vaccine to prevent genital warts in boys and men ages 9-26 years. The agency also has given a thumbs-up to a bivalent HPV vaccine for girls and young women. ann@aafp.org Mon, 19 Oct 2009 17:10:00 CDT Clinical Care & Research New USP Standard for Heparin Decreases Unit Dose Potency, Dictates Careful Monitoring http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091007heparin.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091007heparin.html The FDA is alerting physicians about a change in heparin manufacturing that likely will decrease the potency of the widely used anticoagulant by 10 percent. FDA officials said the U.S. Pharmacopeia, or USP, monograph for heparin has been revised, in part, because of product contamination in 2007 and 2008 that was associated with adverse events, including deaths. ann@aafp.org Wed, 07 Oct 2009 17:10:00 CDT Clinical Care & Research H1N1 Vaccine Deliveries Begin http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091005h1n1-vacc-deliv.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20091005h1n1-vacc-deliv.html The first wave of vaccine against the novel influenza A (H1N1) virus is expected to be delivered to vaccinators beginning the week of Oct. 5-9, according to Anne Schuchat, M.D., director of the CDC's National Center for Immunization and Respiratory Diseases. dmitchell@aafp.org Mon, 05 Oct 2009 17:00:00 CDT Clinical Care & Research One Dose of H1N1 Vaccine Immunogenic in High Percentage of Youth Ages 10 to 17 http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20090930kids-h1n1-trial.html http://www.aafp.org/online/en/home/publications/news/news-now/clinical-care-research/20090930kids-h1n1-trial.html Kids and teenagers 10 years to 17 years old likely will need only one dose of vaccine to protect them against the novel influenza A (H1N1) virus. Younger children, however, probably will need two doses, according to preliminary data from a clinical trial sponsored by the NIH's National Institute of Allergy and Infectious Diseases, or NIAID. dmitchell@aafp.org Wed, 30 Sep 2009 16:55:00 CDT Clinical Care & Research Vaccines & Immunizations Special Report http://www.aafp.org/online/en/home/publications/news/news-now/vaccine.html http://www.aafp.org/online/en/home/publications/news/news-now/vaccine.html This AAFP News Now special report offers an in-depth look at immunizations commonly administered by family physicians, covering such issues as vaccine pricing and associated costs; uptake rates for specific vaccines among various patient groups; the role of registries in boosting immunization numbers; how to handle parents' concerns about vaccinations; and the nation's preparations for a resurgence of the novel influenza A (H1N1) virus this fall. Tue, 04 Aug 2009 16:40:00 CDT Clinical Care & Research