Clinical Preventive Service Recommendation

Cervical Cancer

The AAFP recommends screening for cervical cancer in women age 21 to 65 years with cytology (Pap smear) every 3 years or, for women age 30 to 65 years who want to lengthen the screening interval, screening with a combination of cytology and human papillomavirus (HPV) testing every 5 years. (2012)

(Grade: A recommendations)
(Grade Definition: http://www.uspreventiveservicestaskforce.org/uspstf/grades.htm#arec(www.uspreventiveservicestaskforce.org))
(Clinical Considerations: http://www.uspreventiveservicestaskforce.org/uspstf11/cervcancer/cervcancerrs.htm#clinical(www.uspreventiveservicestaskforce.org))

The AAFP recommends against screening for cervical cancer in women younger than age 21 years. (2012)

(Grade: D recommendation)
(Grade Definition: http://www.uspreventiveservicestaskforce.org/uspstf/grades.htm#arec(www.uspreventiveservicestaskforce.org))
(Clinical Considerations: http://www.uspreventiveservicestaskforce.org/uspstf11/cervcancer/cervcancerrs.htm#clinical(www.uspreventiveservicestaskforce.org))

The AAFP recommends against screening for cervical cancer in women older than age 65 years who have had adequate prior screening and are not otherwise at high risk for cervical cancer. See the Clinical Considerations for discussion of adequacy of prior screening and risk factors. (2012)

(Grade: D recommendation)
(Grade Definition: http://www.uspreventiveservicestaskforce.org/uspstf/grades.htm#arec (www.uspreventiveservicestaskforce.org)
(Clinical Considerations: http://www.uspreventiveservicestaskforce.org/uspstf11/cervcancer/cervcancerrs.htm#clinical(www.uspreventiveservicestaskforce.org))

The AAFP recommends against screening for cervical cancer in women who have had a hysterectomy with removal of the cervix and who do not have a history of a high-grade precancerous lesion (cervical intraepithelial neoplasia [CIN] grade 2 or 3) or cervical cancer. (2012)

(Grade: D recommendation)
(Grade Definition: http://www.uspreventiveservicestaskforce.org/uspstf/grades.htm#arec(www.uspreventiveservicestaskforce.org))
(Clinical Considerations: http://www.uspreventiveservicestaskforce.org/uspstf11/cervcancer/cervcancerrs.htm#clinical(www.uspreventiveservicestaskforce.org))

The AAFP recommends against screening for cervical cancer with HPV testing, alone or in combination with cytology, in women younger than age 30 years. (2012)

(Grade: D recommendation)
Grade Definition: http://www.uspreventiveservicestaskforce.org/uspstf/grades.htm#arec (www.uspreventiveservicestaskforce.org)
Clinical Considerations: http://www.uspreventiveservicestaskforce.org/uspstf11/cervcancer/cervcancerrs.htm#clinical(www.uspreventiveservicestaskforce.org))


These recommendations are provided only as assistance for physicians making clinical decisions regarding the care of their patients. As such, they cannot substitute for the individual judgment brought to each clinical situation by the patient's family physician. As with all clinical reference resources, they reflect the best understanding of the science of medicine at the time of publication, but they should be used with the clear understanding that continued research may result in new knowledge and recommendations. These recommendations are only one element in the complex process of improving the health of America. To be effective, the recommendations must be implemented.