Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Guideline from the American College of Physicians

AAFP Endorsement of Guidelines for Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline from the American College of Physicians

 

The AAFP has reviewed and endorsed this guideline: Oral Pharmacologic Treatment of Type 2 Diabetes Mellitus: A Clinical Practice Guideline from the American College of Physicians.(annals.org)

(Grade: strong recommendation; high-quality evidence)
The American College of Physicians recommends that clinicians add oral pharmacologic therapy in patients diagnosed with type 2 diabetes when lifestyle modifications, including diet, exercise, and weight loss, have failed to adequately improve hyperglycemia.

(Grade: strong recommendation; high-quality evidence)
The American College of Physicians recommends that clinicians prescribe monotherapy with metformin for initial pharmacologic therapy to treat most patients with type 2 diabetes.

(Grade: strong recommendation; high-quality evidence)
The American College of Physicians recommends that clinicians add a second agent to metformin to treat patients with presistent hyperglycemia when lifestyle modifications and monotherapy with metformin fail to control hyperglycemia.

(Endorsed May 2013)