The BioFire FilmArray gastrointestinal (GI) panel is a multiplex polymerase chain reaction (PCR) test approved by the U.S. Food and Drug Administration to assess for 22 common viral, bacterial, and parasitic gastrointestinal pathogens.¹ Stool culture, Clostridioides difficile toxin assay, or ova and parasite testing are typically reserved for patients with severe or prolonged disease, possible C. difficile infection, or unique risks for parasitic infection, respectively.^2,3 In most patients with acute gastroenteritis, testing for a specific etiology is not performed, and confirmation of the pathogen does not change management of self-limited illness.