Correction

Sep 15, 2001 Issue

Correction

Am Fam Physician. 2001 Sep 15;64(6):927-928.

Table 2 of the article “Topical Fluoroquinolones for Eye and Ear” (October 15, 2000, page 1872) contained an error regarding the recommended use of the topical medication ciprofloxacin-hydrocortisone (Cipro HC). The table incorrectly states that Cipro HC, a nonsterile solution, is recommended for use in patients with acute otitis externa and acute otitis media with tympanic membrane perforation. According to the 55th edition of the Physicians’ Desk Reference, the use of Cipro HC is actually contraindicated in patients with a perforated tympanic membrane. However, the table correctly indicates that Floxin, a 0.3 percent sterile solution of ofloxacin, is indicated for use in patients with acute otitis externa, chronic suppurative otitis media with perforations and acute otitis media with tympanostomy tubes. The corrected table is reprinted above.

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TABLE 2

Recommended Treatment Regimens for Ear Infections

Condition	Drug	Dosage*	Duration	Cost†
Acute otitis externa	Ciprofloxacin-hydrocortisone (Cipro HC)	Adult: 3 drops, twice daily	7 to 10 days	$59.00‡/10 mL
	Ciprofloxacin-hydrocortisone (Cipro HC)	Child: 3 drops, twice daily	7 to 10 days	$59.00‡/10 mL
	Ofloxacin(Floxin)	Adult: 10 drops, twice daily	7 to 10 days	34.00‡/5 mL
	Ofloxacin(Floxin)	Child: 5 drops, twice daily	7 to 10 days	34.00‡/5 mL
	Polymyxin B– neomycin– hydrocortisone§ (Cortisporin)	Adult: 5 drops, three to four times daily	7 to 10 days	Brand: 42.00 (solution or suspension)/10 mL
	Polymyxin B– neomycin– hydrocortisone§ (Cortisporin)	Child: 4 drops, three to four times daily	7 to 10 days	Generic: 10.00 to 28.00/10 mL
Acute otitis media with tympanostomy tubes	Ofloxacin	Adult: 5 drops, twice daily	10 to 14 days	Same as above
	Ofloxacin	Child: 5 drops, twice daily	10 to 14 days	Same as above
	Polymyxin B– neomycin– hydrocortisone§	Adult: 5 drops, three to four times daily	10 to 14 days	Same as above
	Polymyxin B– neomycin– hydrocortisone§	Child: 4 drops, three to four times daily	10 to 14 days	Same as above
Chronic suppurative otitis media	Ofloxacin	Adult: 10 drops, twice daily	14 to 21 days	Same as above
	Ofloxacin	Child: 5 drops, twice daily	14 to 21 days	Same as above
	Polymyxin B– neomycin– hydrocortisone§	Not recommended		Same as above

*—Adult = 12 years and older; child = one to 11 years.

†—Costs are given for one-bottle supply. Estimated cost to pharmacist based on average wholesale prices, rounded to nearest dollar amount in Red book. Montvale, NJ: Medical Economics Data, 2000.

‡—Generic not available.

§—Examples: Cortisporin, Colymycin, Pediotic.

TABLE 2

Recommended Treatment Regimens for Ear Infections

Condition	Drug	Dosage*	Duration	Cost†
Acute otitis externa	Ciprofloxacin-hydrocortisone (Cipro HC)	Adult: 3 drops, twice daily	7 to 10 days	$59.00‡/10 mL
	Ciprofloxacin-hydrocortisone (Cipro HC)	Child: 3 drops, twice daily	7 to 10 days	$59.00‡/10 mL
	Ofloxacin(Floxin)	Adult: 10 drops, twice daily	7 to 10 days	34.00‡/5 mL
	Ofloxacin(Floxin)	Child: 5 drops, twice daily	7 to 10 days	34.00‡/5 mL
	Polymyxin B– neomycin– hydrocortisone§ (Cortisporin)	Adult: 5 drops, three to four times daily	7 to 10 days	Brand: 42.00 (solution or suspension)/10 mL
	Polymyxin B– neomycin– hydrocortisone§ (Cortisporin)	Child: 4 drops, three to four times daily	7 to 10 days	Generic: 10.00 to 28.00/10 mL
Acute otitis media with tympanostomy tubes	Ofloxacin	Adult: 5 drops, twice daily	10 to 14 days	Same as above
	Ofloxacin	Child: 5 drops, twice daily	10 to 14 days	Same as above
	Polymyxin B– neomycin– hydrocortisone§	Adult: 5 drops, three to four times daily	10 to 14 days	Same as above
	Polymyxin B– neomycin– hydrocortisone§	Child: 4 drops, three to four times daily	10 to 14 days	Same as above
Chronic suppurative otitis media	Ofloxacin	Adult: 10 drops, twice daily	14 to 21 days	Same as above
	Ofloxacin	Child: 5 drops, twice daily	14 to 21 days	Same as above
	Polymyxin B– neomycin– hydrocortisone§	Not recommended		Same as above

*—Adult = 12 years and older; child = one to 11 years.

†—Costs are given for one-bottle supply. Estimated cost to pharmacist based on average wholesale prices, rounded to nearest dollar amount in Red book. Montvale, NJ: Medical Economics Data, 2000.

‡—Generic not available.

§—Examples: Cortisporin, Colymycin, Pediotic.

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