Am Fam Physician. 2012 May 15;85(10):950.


In the “Cochrane for Clinicians” titled “Opioid Antagonists for the Treatment of Alcohol Dependence” (November 1, 2011, page 990), the relative risk and confidence interval for oral naltrexone reducing the risk of return to heavy drinking were incorrect in the second paragraph of the right-hand column on page 990 and in the abstract on page 991. The text should have read: “Compared with placebo, oral naltrexone reduced the risk of return to heavy drinking by 17 percent (relative risk [RR] = 0.83; 95% confidence interval [CI], 0.76 to 0.90)….” In the “Main Results” section of the abstract, the first sentence should have read: “Based on a total of 50 randomized controlled trials with 7,793 patients, naltrexone reduced the risk of heavy drinking to 83 percent of the risk in the placebo group (relative risk [RR] = 0.83; 95% confidence interval [CI], 0.76 to 0.90)….” The online version of this article has been corrected.



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