Practice Guidelines

ACIP Approves 2019 Adult and Childhood/Adolescent Immunization Schedules


Am Fam Physician. 2019 Feb 15;99(4):264-265.

Author disclosure: No relevant financial affiliations.

Key Points for Practice

• The 2018–2019 influenza vaccination recommendations include inactivated influenza vaccines, recombinant influenza vaccine, and live attenuated influenza vaccine to be administered without preference in age-appropriate patients without contraindications.

• HepB-CpG is recommended for use in nonpregnant people 18 years and older.

• Hepatitis A vaccine is recommended for people experiencing homelessness.

From the AFP Editors

The 2019 adult and childhood/adolescent immunization schedules have been approved by the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention (CDC) and are accessible at The new look includes fewer colors, improved readability, and harmonization between schedules, with several edits to tables. Footnotes will now be called notes and printed in a larger font. Content changes to the notes for hepatitis A; hepatitis B; inactivated polio; measles, mumps, and rubella; meningococcal; and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines will be incorporated.

Influenza Vaccines

Following a particularly severe 2017–2018 influenza season with a record-breaking estimated 900,000 hospitalizations and more than 80,000 deaths in the United States, the National Foundation for Infectious Diseases, with other public health and medical organizations, presented the benefits of influenza vaccination and urged the public and health care professionals to follow the CDC recommendation that everyone six months and older get vaccinated each year.1

The most notable change for the 2019 influenza vaccine recommendations is the addition of quadrivalent live attenuated influenza vaccine to the list of licensed, recommended, and age-appropriate vaccines, including inactivated influenza vaccines, recombinant influenza vaccine, and live attenuated influenza vaccine, to be given without preference for those

Address correspondence to Pamela G. Rockwell, DO, FAAFP, at Reprints are not available from the author.

Author disclosure: No relevant financial affiliations.


show all references

1. National Foundation for Infectious Diseases. Influenza and pneumococcal disease can be serious, health officials urge vaccination. September 2018. Accessed December 23, 2018....

2. Grohskopf LA, Sokolow LZ, Broder KR, Walter EB, Fry AM, Jernigan DB. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices—United States, 2018–19 influenza season. MMWR Recomm Rep. 2018;67(3):1–20.

3. Kroger AT, Duchin J, Vázquez M. General best practice guidelines for immunization: best practices guidance of the Advisory Committee on Immunization Practices (ACIP). Accessed December 23, 2018.

4. Schillie S, Harris A, Link-Gelles R, Romero J, Ward J, Nelson N. Recommendations of the Advisory Committee on Immunization Practices for use of a hepatitis B vaccine with a novel adjuvant. MMWR Morb Mortal Wkly Rep. 2018;67(15):455–458.

5. American Academy of Family Physicians. ACIP recommends hep A vaccine for homeless patients: group discusses pneumococcal vaccine coverage, redesigns immunization schedules. October 2018. Accessed December 23, 2018.

Coverage of guidelines from other organizations does not imply endorsement by AFP or the AAFP.

This series is coordinated by Sumi Sexton, MD, Editor-in-Chief.

A collection of Practice Guidelines published in AFP is available at



Copyright © 2019 by the American Academy of Family Physicians.
This content is owned by the AAFP. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Contact for copyright questions and/or permission requests.

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