Please note: This information was current at the time of publication. But medical information is always changing, and some information given here may be out of date. For regularly updated information on a variety of health topics, please visit, the AAFP patient education website.

Information from Your Family Doctor

Cluster Headache


Am Fam Physician. 2022 Jan ;105(1):online.

  See related article on cluster headaches

What is a cluster headache?

A cluster headache is a rare type of headache that causes pain on one side of the head, often around the eye. These headaches could happen every other day or as often as eight times in a single day. The pain can last from 15 minutes to three hours, and it often comes back around the same time each day.

Are there any other symptoms?

You may notice other changes to your face on the same side as the headache. These include eye watering and redness, stuffy or runny nose, or swelling of the eyelid, forehead, or face. You may have a droopy eyelid or changes in the size of the pupil. You may feel agitated or restless during an attack.

Who gets it?

Cluster headache is more common in men than in women. It usually starts between 20 and 40 years of age. It is more common if you have a relative with cluster headache.

How is it treated?

Treatment starts with avoiding things that trigger the headache. These can include alcohol, tobacco smoke, nitroglycerin (a medicine for certain heart conditions), or things you may be allergic to. Oxygen or prescription medicines are the best treatments to stop the headache once symptoms start.

What can I do to prevent it?

Avoiding the things that trigger your headache is important. It may help to keep a diary of when your symptoms start and what you were doing before they began. Depending on how often you have the headaches, your doctor may prescribe medicines to prevent them from starting.

Where can I get more information?

Your doctor

American Academy of Family Physicians

American Migraine Foundation

National Headache Foundation

National Organization for Rare Disorders - Rare Disease Database

Organization for Understanding Cluster Headaches

The Cluster Headache Support Group

This handout is provided to you by your family doctor and the American Academy of Family Physicians. Other health-related information is available from the AAFP online at

This information provides a general overview and may not apply to everyone. Talk to your family doctor to find out if this information applies to you and to get more information on this subject.


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