Don’t use sputum cytology to evaluate patients with peripheral lung lesions.
|Rationale and Comments:||Sputum cytology is not effective for evaluating peripheral lesions. For peripheral lesion evaluation, consider alternative diagnostic approaches (e.g., image guided needle aspiration).|
|References:||• Demay RM, The Art & Science of Cytopathology. Chicago, IL: ASCP Press; 1996.
• Felten MK, Knoll L, Schikowsky C, et al. Is it useful to combine sputum cytology and low-dose spiral computed tomography for early detection of lung cancer in formerly asbestos-exposed power industry workers? J Occup Med Tox. 2014; 9(14): 1-9.
• Katz RL, Zaidi TM, Fernandez RL, et al. Automated detection of genetic abnormalities combined with cytology in sputum is a sensitive predictor of lung cancer. Mod Pathol. 2008; 21(8): 950-960.
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