Choosing Wisely:

Avoid ordering follow-up urine cultures after treatment for an uncomplicated urinary tract infection in patients that show evidence of clinical resolution of infection.

Rationale and Comments: Studies have shown that clinical resolution of infection is adequate for determining effectiveness of antibiotic therapy after treatment for a urinary tract infection.
Sponsoring Organizations:
  • American Academy of Pediatrics – Section on Nephrology and the American Society of Pediatric Nephrology
  • Sources:
  • American Academy of Pediatrics guidelines
  • Disciplines:
  • Infectious disease
  • Urologic
  • References: • American Academy of Pediatrics, Committee on Quality Improvement, Subcommittee on Urinary Tract Infection. Practice parameter: the diagnosis, treatment, and evaluation of the initial urinary tract infection in febrile infants and young children. Pediatrics. 1999;103:843-852.
    • Bachir R. Nonresponders: prolonged fever among infants with urinary tract infections. Pediatrics. 2000;105:E59.
    • Currie ML, Mitz L, Raasch CS, Greenbaum LA. Follow-up urine cultures and fever in children with urinary tract infection. Arch Pediatr Adolesc Med. 2003;157:1237-1240.
    • Oreskovic NM, Sembrano EU. Repeat urine cultures in children who are admitted with urinary tract infections. Pediatrics. 2007;119(2):e325-329.

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