Choosing Wisely:

Don’t continue antibiotic therapy without evidence of need.

Rationale and Comments: In addition to employing microbe-directed therapy, a core principle of antibiotic stewardship is limiting antimicrobial therapy to the shortest effective duration. As a general rule, antimicrobials should be discontinued when the condition for which they were prescribed has been adequately treated, as one strategy to ensure access to effective antimicrobials at a time when increased antimicrobial resistance represents a global health care challenge.
Sponsoring Organizations:
  • Society of Critical Care Medicine
  • Sources:
  • Centers for Disease Control and Prevention
  • Disciplines:
  • Infectious disease
  • References: • CDC. Core elements of hospital antibiotics stewardship program. Atlanta, GA: US Department of Health and Human Services, CDC, 2019.

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